Fabrication and development of mechanical metamaterials via additive manufacturing for biomedical applications:a review  

作　　者：Junsheng Chen Jibing Chen Hongze Wang Liang He Boyang Huang Sasan Dadbakhsh Paulo Bartolo 

机构地区：[1]School of Mechanical Engineering,Wuhan Polytechnic University,Wuhan 420023,People’s Republic of China [2]School of Materials Science&Engineering,Shanghai Jiao Tong University,Shanghai 200240,People’s Republic of China [3]State Key Laboratory of Metal Matrix Composites,Shanghai Jiao Tong University,Shanghai 200240,People’s Republic of China [4]School of Mechanical Engineering,Sichuan University,Chengdu 610065,People’s Republic of China [5]Med+X Center for Manufacturing,West China Hospital,Sichuan University,Chengdu 610041,People’s Republic of China [6]Singapore Centre for 3D Printing,Nanyang Technological University,Singapore 639798,Singapore [7]School of Mechanical and Aerospace Engineering,Nanyang Technological University,Singapore 639798,Singapore [8]Department of Production Engineering,KTH Royal Institute of Technology,Stockholm 11428,Sweden

出　　处：《International Journal of Extreme Manufacturing》2025年第1期1-44,共44页极端制造(英文)

基　　金：sponsored by the Science and Technology Program of Hubei Province,China(2022EHB020,2023BBB096);support provided by Centre of the Excellence in Production Research(XPRES)at KTH。

摘　　要：In this review,we propose a comprehensive overview of additive manufacturing(AM)technologies and design possibilities in manufacturing metamaterials for various applications in the biomedical field,of which many are inspired by nature itself.It describes how new AM technologies(e.g.continuous liquid interface production and multiphoton polymerization,etc)and recent developments in more mature AM technologies(e.g.powder bed fusion,stereolithography,and extrusion-based bioprinting(EBB),etc)lead to more precise,efficient,and personalized biomedical components.EBB is a revolutionary topic creating intricate models with remarkable mechanical compatibility of metamaterials,for instance,stress elimination for tissue engineering and regenerative medicine,negative or zero Poisson’s ratio.By exploiting the designs of porous structures(e.g.truss,triply periodic minimal surface,plant/animal-inspired,and functionally graded lattices,etc),AM-made bioactive bone implants,artificial tissues,and organs are made for tissue replacement.The material palette of the AM metamaterials has high diversity nowadays,ranging from alloys and metals(e.g.cobalt-chromium alloys and titanium,etc)to polymers(e.g.biodegradable polycaprolactone and polymethyl methacrylate,etc),which could be even integrated within bioactive ceramics.These advancements are driving the progress of the biomedical field,improving human health and quality of life.

关 键 词：biomedical application additive manufacturing mechanical metamaterials biomimetic materials 

分 类 号：TG1[金属学及工艺—金属学]