辅助生殖技术助孕患者妊娠期睡眠发展轨迹及影响因素分析  

Sleep trajectory during pregnancy in patients receiving assisted reproductive technology and its influencing factors

作　　者：李汶莲 饶琳[1,3] 周璇 李红 Li Wenlian;Rao Lin;Zhou Xuan;Li Hong(Nursing Department,The International Peace Maternity and Child Health Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200030,China;School of Nursing,Shanghai Jiao Tong University,Shanghai 200025,China;Shanghai Key Laboratory of Embryo Original Diseases,Shanghai 200030,China)

机构地区：[1]上海交通大学医学院附属国际和平妇幼保健院护理部,上海200030 [2]上海交通大学护理学院,上海200025 [3]上海市胚胎源性疾病重点实验室,上海200030

出　　处：《中华现代护理杂志》2025年第10期1307-1313,共7页Chinese Journal of Modern Nursing

基　　金：国家重点研发计划(2016YFC1000203,2022YFC2702903);上海市护理学会科研课题重点项目(2022SD-B02)。

摘　　要：目的探讨辅助生殖技术助孕患者妊娠期睡眠发展轨迹及其影响因素。方法采用便利抽样法,选取2017年5月—2022年1月在上海交通大学医学院附属国际和平妇幼保健院进行产前检查的1249例辅助生殖技术助孕患者为研究对象,分别在孕12~14周(T1)、孕22~24周(T2)、孕32~34周(T3)采用匹兹堡睡眠质量指数量表评估其睡眠质量。应用潜类别增长模型探索辅助生殖技术助孕患者的妊娠期睡眠发展轨迹,并采用多分类Logistic回归分析探讨睡眠发展轨迹的影响因素。结果本研究共发放问卷1249份,最终回收有效问卷1090份,问卷有效率为87.27%(1090/1249)。1090例辅助生殖技术助孕患者妊娠期睡眠发展轨迹有3种类型,分别为睡眠改善组(7.89%,86/1090)、睡眠恶化组(7.43%,81/1090)、睡眠良好组(84.68%,923/1090)。多分类Logistic回归分析结果显示,年龄、家庭年收入、胚胎移植前服用阿司匹林、呕吐、二手烟暴露、焦虑和抑郁是辅助生殖技术助孕患者睡眠发展轨迹的影响因素(P<0.05)。结论辅助生殖技术助孕患者妊娠期睡眠情况存在差异,医护人员可基于影响因素进行干预,以提高患者妊娠期睡眠质量。Objective To explore the sleep trajectory during pregnancy and its influencing factors in patients receiving assisted reproductive technology(ART).Methods Convenience sampling was used to select 1249 patients with ART who underwent prenatal checkups at the International Peace Maternity and Child Health Hospital,School of Medicine,Shanghai Jiao Tong University from May 2017 to January 2022 as study subjects.The patients'sleep quality was assessed using the Pittsburgh Sleep Quality Index at 12 to 14 weeks of gestation(T1),22 to 24 weeks of gestation(T2),and 32 to 34 weeks of gestation(T3),respectively.The latent class growth model was applied to explore the trajectory of sleep during pregnancy in patients receiving ART,and multicategorical Logistic regression were used to analyze the factors influencing the trajectory of sleep.Results A total of 1249 questionnaires were distributed and 1090 valid questionnaires were finally recovered,with a validity rate of 87.27%(1090/1249).There were three types of sleep trajectories during pregnancy in 1090 patients receiving ART,including sleep improvement group(7.89%,86/1090),sleep deterioration group(7.43%,81/1090),and good sleep group(84.68%,923/1090).Multicategorical Logistic regression analysis showed that age,annual household income,aspirin use before embryo transfer,vomiting,secondhand smoke exposure,anxiety,and depression were influencing factors of the sleep trajectory in patients with ART(P<0.05).Conclusions There are differences in sleep quality during pregnancy among patients with ART.Healthcare professionals can intervene based on the influencing factors to improve sleep quality during pregnancy.

关 键 词：辅助生殖技术 睡眠质量 轨迹 潜类别增长模型 影响因素 

分 类 号：R71[医药卫生—妇产科学]