运动干预在血友病性骨关节病患者康复中应用的范围综述  

Application of exercise interventions in the rehabilitation of patients with hemophilic arthropathy:a scoping review

作　　者：竺晨 史颜凯 徐妍 卫心怡 颜如意 滑东雪 张晓兰[4] Zhu Chen;Shi Yankai;Xu Yan;Wei Xinyi;Yan Ruyi;Hua Dongxue;Zhang Xiaolan(School of Nursing,Zhejiang Chinese Medical University,Hangzhou 310053,China;School of Nursing,Hangzhou Normal University,Hangzhou 311121,China;Joint Diagnosis and Treatment Center,the First Affiliated Hospital of Zhejiang Chinese Medicine University(Zhejiang Provincial Hospital of Chinese Medicine),Hangzhou 310006,China;Nursing Department,the First Affiliated Hospital of Zhejiang Chinese Medicine University(Zhejiang Provincial Hospital of Chinese Medicine),Hangzhou 310006,China)

机构地区：[1]浙江中医药大学护理学院,杭州310053 [2]杭州师范大学护理学院,杭州311121 [3]浙江中医药大学附属第一医院(浙江省中医院)关节病诊疗中心,杭州310006 [4]浙江中医药大学附属第一医院(浙江省中医院)护理部,杭州310006

出　　处：《中华现代护理杂志》2025年第10期1388-1395,共8页Chinese Journal of Modern Nursing

基　　金：浙江省中医药科技计划(2024ZL472);浙江省医药卫生科技计划(2024KY1206)。

摘　　要：目的对运动干预在血友病性骨关节病患者康复中应用的相关研究进行范围综述。方法计算机检索PubMed、Web of Science、Cochrane Library、Embase、CINAHL、中国知网、万方数据库、维普网及中国生物医学文献数据库,检索时限为建库至2024年3月1日。对纳入文献进行筛选、汇总和分析。结果共纳入31篇文献。研究对象多患有肘、膝及踝关节病,处于出血稳定期且无凝血因子抑制物的中重度成人血友病患者;运动类型包括抗阻运动、有氧运动、平衡/本体感觉运动和柔韧性运动;运动强度以低中强度为主;运动时长多为每次30~60 min,频率多为2~5次/周,周期多为4~12周;运动场所多为医疗机构,监督多为"面对面"方式。运动干预对血友病性骨关节病患者的活动能力、平衡/本体感觉功能、关节功能、心肺功能、心理状态及生活质量有不同程度的改善。结论血友病性骨关节病患者的运动干预类型多样,具有一定的安全性、可行性和有效性。未来应重视以运动为核心的多元化综合康复模式,规范统一评价标准,动态监测全过程,以制订标准化运动康复方案。Objective To conduct a scoping review of studies on the application of exercise interventions in the rehabilitation of patients with hemophilic arthropathy(HA).Methods A systematic search was conducted in PubMed,Web of Science,Cochrane Library,Embase,CINAHL,China National Knowledge Infrastructure,Wanfang Data,VIP,and China Biology Medicine disc.The search period was from the database inception to March 1,2024.Relevant literature was screened,summarized,and analyzed.Results A total of 31 studies were included.The study population mainly consisted of adult patients with moderate to severe hemophilia suffering from elbow,knee,and ankle arthropathy,who were in a stable bleeding phase without coagulation factor inhibitors.Exercise types included resistance training,aerobic exercise,balance/proprioceptive exercises,and flexibility training.The exercise intensity was predominantly low to moderate.The duration of each session was mostly 30-60 minutes,with a frequency of 2-5 times per week and a total intervention period of 4-12 weeks.Exercises were mostly conducted in medical institutions under face-to-face supervision.Exercise interventions led to varying degrees of improvement in mobility,balance/proprioceptive function,joint function,cardiopulmonary fitness,psychological well-being,and quality of life.Conclusions Exercise interventions for patients with hemophilic arthropathy are diverse,demonstrating safety,feasibility,and efficacy.Future research should focus on a multidisciplinary,exercise-centered rehabilitation approach,standardizing evaluation criteria,and dynamically monitoring the rehabilitation process to develop standardized exercise rehabilitation protocols.

关 键 词：综述 血友病性骨关节病 运动 康复 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]