组织芯片在生物样本活库中的应用  

Applications of tissue microarrays in living biobanks

作　　者：陈明敏 CHEN Mingmin

机构地区：[1]生物芯片上海国家工程研究中心/上海芯超生物科技有限公司,201203

出　　处：《中国医药生物技术》2025年第S1期16-18,共3页Chinese Medicinal Biotechnology

摘　　要：随着生物技术的飞速发展,生物样本活库作为生物样本资源的重要储存和管理方式,对于生命科学研究、疾病诊断与治疗等领域具有关键意义。组织芯片技术以其高通量、微型化、样本代表性强等特点,在生物样本活库的构建与样本资源共享中展现出独特的优势和广阔的应用前景。本文详细阐述了组织芯片在生物样本活库与样本资源共享过程中的技术原理、制备方法、质量控制,以及其在生物医学研究、临床诊断、药物研发等方面的应用,并对其未来发展趋势进行展望。With the rapid development of biotechnology,living biobanks,as an essential means of storing and managing biological samples,have become crucial for life science research,disease diagnosis,treatment,etc.Tissue microarray(TMA),characterized by its high-throughput,miniaturization,strong sample representation,etc,has demonstrated unique advantages and broad application prospects in the construction of biobanks and the sharing of sample resources.This review provides a comprehensive overview of the technical principles,preparation methods,and quality control measures of tissue microarrays in the context of living biobanks and sample sharing.Additionally,we discuss the applications of tissue microarrays in biomedical research,clinical diagnostics,drug development,etc.Finally,we offer insights into the future development trends of the technology.

关 键 词：组织芯片 生物样本活库 质量控制 

分 类 号：Q813[生物学—生物工程]