国医大师治疗不寐用药规律  

Medication Law of National TCM Masters in Treating Insomnia

作　　者：张舒琪 张琪 程婷 刘丽红[1] ZHANG Shuqi;ZHANG Qi;CHENG Ting;LIU Lihong(Institute of Information on Traditional Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]中国中医科学院中医药信息研究所,北京100700

出　　处：《中国中医药图书情报杂志》2025年第2期39-43,共5页Chinese Journal of Library and Information Science for Traditional Chinese Medicine

基　　金：中国中医科学院科技创新工程重大攻关项目(CI2021A05409);中国中医科学院基本科研业务费自主选题项目(ZZ170326、ZZ180305)。

摘　　要：目的 利用数据挖掘技术分析国医大师治疗不寐的用药规律。方法 检索中国知识资源总库(CNKI)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)、中文科技期刊数据库(VIP)建库至2023年11月30日收录的国医大师治疗不寐文献,建立处方数据库,运用Excel2017分析药物频次、功效及性味归经,利用古今医案云平台2.3.5进行关联规则分析和系统聚类分析。结果 纳入有效处方335首,涉及中药308味,高频药物为酸枣仁、茯苓、甘草、当归、柴胡、炙甘草、白芍等;药物类型以润肠通便药、宁心安神药、燥湿化痰药为主;药性以平、温为主;药味以甘、苦为主;归经以心经、肝经为主。关联规则得出17组核心药物组合,聚类分析将高频药物分为2类。结论 国医大师治疗不寐以养心安神、疏肝健脾为关键治法,用药以安神类为主,还多用润肠通便类、燥湿化痰类药,常用酸枣仁汤、逍遥散、天王补心丹。Objective To discuss the medication law of national TCM masters in treating insomnia based on data mining methods.Methods The clinical research literature about national TCM masters in treating insomnia was retrieved from CNKI,Wangfang Data,CBM and VIP from the establishment of the databases to November 30,2023.A database of screened prescriptions was established.Analysis on frequency,efficacy,property and taste,and meridian was performed by Excel 2017.Association rule analysis and systematic clustering analysis of drugs were performed through the Ancient and Modern Medical Case Cloud Platform 2.3.5.Results Totally 335 effective prescriptions were included,involving 308 kinds of Chinese materia medica.The drugs with high frequency of use were Ziziphi Spinosae Semen,Poria,Glycyrrhizae Radix et Rhizoma,Angelicae Sinensis Radix,Bupleuri Radix,Glycyrrhizae Radix et Rhizoma Praeparata cum Melle,Paeoniae Radix alba,etc.;the main types of drugs were moistening the intestines and relieving constipation,calming the heart and the mind,and eliminating dampness and phlegm;the drug properties were mainly neutral and warm;the tastes were mainly sweet and bitter;the meridians were mainly the heart and liver meridians.17 core medicinal pairs were obtained by association rules,and high frequency drugs were divided into 2 categories by clustering analysis.Conclusion National TCM masters treat insomnia based on the principles of nourishing the heart and calming the mind,soothing the liver and strengthening the spleen.In addition to using calming herbs,they also make good use of drugs such as moistening the intestines and relieving constipation and eliminating dampness and phlegm.Commonly used prescriptions are Suanzaoren Decoction,Xiaoyao Powder and Tianwang Buxin Decoction.

关 键 词：国医大师 不寐 失眠 难眠 用药规律 

分 类 号：R256.23[医药卫生—中医内科学]