经皮血管内支架置入术治疗下肢闭塞性动脉硬化的效果及对踝肱指数和不良事件发生的影响  

Effect of percutaneous endovascular stent placement in treatment of lower limb arteriosclerosis obliterans and its impact on ankle brachial index and adverse events

作　　者：谢方涛 李福山 李晓光[1] 罗海平 XIE Fangtao;LI Fushan;LI Xiaoguang;LUO Haiping(Department of Vascular Surgery,Sanming First Hospital,Sanming 365000,Fujian,China)

机构地区：[1]三明市第一医院血管外科,福建三明365000

出　　处：《外科研究与新技术(中英文)》2025年第1期48-51,共4页Surgical Research and New Technique

摘　　要：目的 分析经皮血管内支架置入术用于治疗下肢闭塞性动脉硬化(ASO)的效果及对踝肱指数和不良事件发生的影响。方法 选取2021年1月—2023年12月期间收治的68例下肢ASO患者为研究对象,采用随机数字表法分为观察组(n=34)和对照组(n=34),分别采用经皮血管内支架置入术和经皮腔内血管成形术治疗。分别于术前和术后6个月测定患者足背动脉、胫后动脉踝肱指数,足背动脉血流指标、血管内径,计算术后6个月治疗相关不良事件发生率,并进行组间比较。结果 (1)两组治疗后足背动脉和胫后动脉的踝肱指数均较治疗前升高,且观察组显著高于对照组,差异均有统计学意义(P<0.05);(2)观察组和对照组治疗后足背动脉血流峰速、血流量、血管内径均较治疗前升高(P<0.05),但两组间差异无统计学意义(P>0.05);(3)治疗相关不良事件发生率在观察组和对照组间比较,差异无统计学意义(P>0.05)。结论 经皮血管内支架置入术可更好地改善下肢ASO患者下肢动脉缺血状态,有利于加快患者康复,且术后不良事件发生率较低,治疗安全性有保障。Objective To analyze the impact of percutaneous endovascular stent placement in the treatment of lower limb arteriosclerosis obliterans(ASO)and its effect on ankle brachial index and adverse events.Methods A total of 68 patients with lower limb ASO from January 2021 to December 2023 were included as study subjects.All the patients were randomly divided into an observation group(percutaneous endovascular stenting,n=34)and a control group(percutaneous angioplasty,n=34)by random number table method.The differences in ankle brachial index of dorsalis pedis artery,ankle brachial index of posterior tibial artery,blood flow index of dorsalis pedis artery,vascular diameter,and incidence of treatment-related adverse events were compared between the two groups.Results(1)The ankle brachial index of dorsalis pedis artery and the ankle brachial index of posterior tibial artery in the two groups after treatment were higher than those before treatment,and the observation group presented higher index values than the control group(P<0.05).(2)The peak blood flow velocity,blood flow,and diameter of the dorsalis pedis artery after treatment in both groups were higher than those before treatment(P<0.05),but no difference was found between the two groups(P>0.05).(3)There was no significant difference in the incidence of treatment-related adverse events between the two groups(P>0.05).Conclusion Percutaneous endovascular stent placement can better improve lower extremity arterial ischaemia than percutaneous angioplasty in patients with lower limb ASO,which is beneficial for accelerating patient recovery,and the incidence of postoperative adverse events is low,ensuring treatment safety.

关 键 词：经皮血管内支架置入术 经皮腔内血管成形术 闭塞性动脉硬化 下肢 踝肱指数 不良事件 

分 类 号：R658[医药卫生—外科学]