抹茶刺梨软胶囊的制备工艺研究  

Study on the Preparation Process of Matcha Rosa Roxburghii Tratt Soft Capsule

作　　者：梁增彩 田应刚 唐伟 张建康 白志文 LIANG Zengcai;TIAN Yinggang;TANG Wei;ZHANG Jiankang;BAI Zhiwen(College of Medicine,Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China;Gui Zhou Wucha Great Health Industry Development Co.,Ltd.,Guiyang 550000,China;Guizhou Tongren Guicha Tea Industry Co.,Ltd.,Tongren 554300,China)

机构地区：[1]贵州中医药大学药学院,贵州贵阳550025 [2]贵州吾茶大健康产业发展有限公司,贵州贵阳550000 [3]贵州铜仁贵茶茶业股份有限公司,贵州铜仁554300

出　　处：《中国茶叶加工》2025年第1期18-22,共5页China Tea Processing

基　　金：黔科合支撑[2022]重点011号。

摘　　要：试验研究了抹茶刺梨软胶囊的制备工艺,采用单因素试验和正交试验方法,筛选软胶囊内容配方、囊壳配方及干燥条件参数,确定抹茶刺梨软胶囊的最佳工艺。结果表明,抹茶刺梨软胶囊内容物的最佳处方配比为抹茶粉∶刺梨冻干粉∶铁皮石斛粉∶山茶油=10∶10∶5∶24,蜂蜡加入量为内容物的2.0%;抹茶刺梨软胶囊囊壳的最佳配比为明胶∶甘油∶水=3∶2∶5;溶胶温度70℃,软胶囊最佳干燥温度30℃,干燥时间10~12 h;3批中试成品率≥95%,崩解时限符合要求。优化的软胶囊制备工艺合理可行,为抹茶刺梨软胶囊制备提供了参考和依据。This study investigates the optimized preparation process of matcha Rosa Roxburghii Tratt soft capsules,utilizing single-factor experiments and orthogonal experimental methods to screen the formulation of the soft capsule contents,the capsule shell formulation,and drying conditions.The aim was to determine the optimal preparation for matcha Rosa Roxburghii Tratt soft capsules.The results showed that the best formula for the soft capsule content was Matcha powder:Rosa roxburghii freeze-dried powder∶Dendrobium candidum powder∶Camellia oil=10∶10∶5∶24,with beeswax added at 2.0%of the total content.The best formula for the capsule shell was gelatin∶glycerol∶water=3∶2∶5,with a sol temperature of 70℃,and the optimal drying temperature was 30℃,with a drying time of 10-12 hours.The yield for three pilot batches was≥95%,and the disintegration time met the required standards.The optimized preparation process of soft capsules was reasonable and feasible,providing a basis for controllable production processes and consistent quality.

关 键 词：抹茶刺梨软胶囊 制备工艺 正交试验 崩解时限 

分 类 号：TS218[轻工技术与工程—粮食、油脂及植物蛋白工程]