难治性肺炎支原体肺炎学龄期儿童的胸部CT特点与肺功能变化的相关性研究  

Study on the correlation between chest CT characteristics and lung function changes in school-age children with refractory mycoplasma pneumoniae pneumonia

作　　者：陈清凤 钟豪文 邵春玲 蔡锋铭 CHEN Qingfeng;ZHONG Haowen;SHAO Chunling;CAI Fengming(Department of Pediatrics,Kaiping Central Hospital,Jiangmen 529300,China)

机构地区：[1]开平市中心医院儿科,广东江门529300

出　　处：《延边大学医学学报》2025年第2期82-84,共3页Journal of Medical Science Yanbian University

基　　金：江门市医疗卫生领域科技计划项目(编号:2023YL10009)。

摘　　要：目的:探讨难治性肺炎支原体肺炎(RMPP)学龄期儿童的胸部CT特点与肺功能变化的相关性。方法:选取开平市中心医院于2023年5月至2024年10月收治的120例RMPP学龄期儿童进行研究,根据胸部CT检查的结果,将患儿分为磨玻璃样改变组、实变组、斑片组,每组各40例。对比三组肺通气功能指标、三组中累及不同数目肺叶患儿肺通气功能及RMPP患儿胸部CT特点与肺通气功能变化的相关性。结果:磨玻璃样改变组和实变组患儿的用力肺活量(FVC)、第1秒用力呼气容积(FEV_(1))、第1秒用力呼气容积占用力肺活量的百分比(FEV_(1)/FVC)、呼气峰流量(PEF)、呼出25%~75%肺活量时用力呼气流量(FEF25%~75%)及用力呼出25%~75%肺活量之间的平均流量(MMEF)均低于斑片组患儿(P <0.05);除了FEV_(1)/FVC、FEF25%~75%及MMEF,磨玻璃样改变组患儿的FVC、FEV_(1)、PEF均高于实变组患儿(P <0.05);磨玻璃样改变组中累及肺叶≥2个患儿的FVC、FEV_(1)、FEV_(1)/FVC、PEF、FEF25%~75%以及MMEF均显著低于累及1个肺叶的患儿(P <0.05);实变组中累及肺叶≥2个的患儿各项指标均明显高于累及1个肺叶的患儿(P <0.05);除了PEF,斑片组中累及肺叶≥2个患儿的其他各项指标均低于累及1个肺叶的患儿(P <0.05);RMPP患儿胸部CT特点与各项肺通气功能指标均呈正相关(P <0.05)。结论:RMPP学龄期儿童的胸部CT表现与肺通气功能之间存在明显的相关性,不同胸部CT表现、累及不同数目肺叶患儿的肺通气功能存在差异。Objective:To explore the correlation between chest CT characteristics and lung function changes in school aged children with refractory Mycoplasma pneumoniae pneumonia(RMPP).Methods:A total of 120 school-age children with RMPP admitted to Kaiping Central Hospital from May 2023 to October 2024 were selected and divided into three groups according to the results of chest CT examination:a ground-glass change group,a consolidation group,and a patchy group,with 40 cases in each group.The pulmonary ventilation function index,pulmonary ventilation function in children with different number of lung lobes involved,and the correlation between chest CT characteristics and changes in lung ventilation function in children with RMPP were compared among the three groups.Results:The forced vital capacity(FVC),forced expiratory volume in one second(FEV1),the percentage of forced expiratory volume in one second to forced vital capacity(FEV_(1)/FVC),peak expiratory flow(PEF),forced expiratory flow when exhaling 25%to 75%of lung capacity(FEF 25%to 75%),and the average flow rate between forced expiratory 25%to 75%of lung capacity(Maximal Mid-Expiratory Flow,MMEF)in the ground-glass change group and consolidation group were all lower than those in the patchy group(P<0.05).Except for FEV1/FVC,FEF25%-75%and MMEF,FVC,FEV1and PEF in the ground-glass change group were higher than those in the consolidation group(P<0.05).The FVC,FEV_(1),FEV_(1)/FVC,PEF,FEF25%to 75%,and MMEF of children with involvement of≥2 lung lobes in the ground-glass change group were significantly lower than those of children with involvement of 1 lung lobe(P<0.05).In the consolidation group,the indexes of children with≥2 lung lobes involved were significantly higher than those with 1 lung lobe involved(P<0.05).Except for PEF,the other indexes of children with≥2 lung lobes involved in the patchy group were lower than those of children with 1 lung lobe involved(P<0.05).There was a positive correlation between the features of chest CT and the indexes of pulmonary v

关 键 词：难治性肺炎支原体肺炎 学龄期儿童 胸部CT特点 肺通气功能 

分 类 号：R725.6[医药卫生—儿科]