甲泼尼龙琥珀酸钠治疗儿童重症支原体肺炎的疗效分析  

Efficacy Analysis of Methylprednisolone Sodium Succinate in the Treatment of Severe Mycoplasma Pneumonia in Children

作　　者：亚克普·艾海提 买地努尔·阿哈提 玛依热·买合木提 Yakefu·Aihaiti;Maidinuer·Ahati;Mayire·Maihemuti(Beijing Children's Hospital,Xinjiang Hospital(Xinjiang Uygur Autonomous Region Children's Hospital),Urumqi 831399,China)

机构地区：[1]北京儿童医院新疆医院(新疆维吾尔自治区儿童医院),新疆乌鲁木齐831399

出　　处：《延边大学医学学报》2025年第2期105-107,共3页Journal of Medical Science Yanbian University

摘　　要：目的:探讨甲泼尼龙琥珀酸钠治疗儿童重症支原体肺炎的临床疗效。方法:于2023年1月至2024年6月,从北京儿童医院新疆医院选取120例重症支原体肺炎患儿参与研究,并利用随机数表法将其分为观察组和对照组,每组60例。两组均实施常规治疗,观察组增加使用甲泼尼龙琥珀酸钠治疗。记录两组炎性因子指标的水平及治疗的总有效率。结果:治疗后,观察组的C反应蛋白(CRP)和降钙素原(PCT)水平低于对照组(P <0.05)。观察组治疗的总有效率为96.67%,而对照组治疗的总有效率为85.00%,观察组高于对照组(P <0.05)。结论:甲泼尼龙琥珀酸钠治疗儿童重症支原体肺炎能获得显著的疗效,有助于促进肺部炎症的消退。Objective:To investigate the clinical efficacy of methylprednisolone sodium succinate in the treatment of severe mycoplasma pneumonia(SMP)in children.Methods:From January 2023 to June 2024,120 children with SMP admitted to Beijing Children's Hospital,Xinjiang Hospital were enrolled and randomly divided into an observation group and a control group using a random number table,with 60 cases in each group.Both groups received conventional therapy,while the observation group was additionally treated with methylprednisolone sodium succinate.Levels of inflammatory markers(CRP and PCT)and the total effective rate of treatment were recorded and compared between the two groups.Results:After treatment,CRP and PCT levels in the observation group were significantly lower than those in the control group(P<0.05).The total effective rate in the observation group was 96.67%,significantly higher than 85.00%in the control group(P<0.05).Conclusion:Methylprednisolone sodium succinate demonstrates significant efficacy in treating severe mycoplasma pneumonia in children,effectively promoting the resolution of pulmonary inflammation.

关 键 词：重症支原体肺炎 甲泼尼龙琥珀酸钠 儿童 

分 类 号：R725.6[医药卫生—儿科]