参苓白术口服液对肉鸡生长性能与免疫和肠道结构及功能的影响  

Effects of Shenling Baizhu Oral Liquid on Growth Performance,Immunity,Intestinal Structure and Function of Broilers

作　　者：崔婵婵 张琼一 张世佳 王霄 杜西翠 史万玉[1,3] 包永占 陈福星[1] CUI Chan-chan;ZHANG Qiong-yi;ZHANG Shi-jia;WANG Xiao;DU Xi-cui;SHI Wan-yu;BAO Yong-zhan;CHEN Fu-xing(College of Traditional Chinese Veterinary Medicine,Hebei Agricultural University,Baoding,Hebei 071000,China;Hebei Jinkun Animal Pharmaceutical Co.,Ltd.,Xinji,Hebei 253011,China;Hebei Provincial Engineering Research Center of Traditional Chinese Veterinary Medicine,Baoding,Hebei 071000,China)

机构地区：[1]河北农业大学中兽医学院,河北保定071000 [2]河北锦坤动物药业有限公司,河北辛集052300 [3]河北省中兽药技术创新中心,河北保定071000

出　　处：《动物医学进展》2025年第5期23-30,共8页Progress In Veterinary Medicine

基　　金：“十四五”国家重点研发计划项目(2022YFD1801104);河北省现代农业产业技术体系创新团队建设专项(HBCT2024110202);河北省重点研发计划资助项目(22326622D)。

摘　　要：试验旨在研究参苓白术口服液对肉鸡生长性能、免疫力、肠道结构及功能的影响。将肉鸡随机分成空白对照组,正常饮水;黄芪多糖对照组,在饮水中加入0.8 mL/L的黄芪多糖口服液(Huangqi polysaccharide oral liquid,HPS);参苓白术口服液低、中、高剂量组,分别在饮水中加入1.5、3.0、4.5 mL/L的参苓白术口服液。试验周期42 d,采集肉鸡血清和肠道组织样品,检测相关指标。结果表明,与空白对照组比较,1~42日龄中剂量组和高剂量组的平均日增重显著增加(P<0.05),料重比显著降低(P<0.05)。21日龄时,中剂量组的脾脏指数显著增加(P<0.05);中剂量组和高剂量组的IgA含量显著增加(P<0.05);中剂量组十二指肠的绒毛高度、绒隐比显著增加(P<0.05),隐窝深度显著降低(P<0.05);黄芪多糖组、中剂量组和高剂量组的十二指肠α-淀粉酶以及空肠脂肪酶含量显著升高(P<0.05);黄芪多糖组、中剂量组和高剂量组的粗脂肪和粗蛋白显著增加(P<0.05)等。42日龄时,黄芪多糖组和中剂量组的脾脏指数显著升高(P<0.05);中剂量组和高剂量组的IgA、IgG含量显著升高(P<0.05);黄芪多糖组、中剂量组和高剂量组十二指肠以及空肠的绒隐比显著增加(P<0.05),隐窝深度显著降低(P<0.05)。研究表明,参苓白术口服液可以提高肉鸡的生长性能、免疫力以及肠道功能,其中以添加3 mL/L的参苓白术口服液为最佳。This experiment was conducted to study the effects of Shenling Baizhu oral liquid on growth performance,immunity,intestinal structure and function of broilers.Broilers were randomly divided into a blank control group,which drank water normally.In the control group,0.8 mL/L Huangqi polysaccharide oral liquid(HPS)was added into the drinking water;In low,medium and high dose groups,1.5,3 and 4.5 mL/L of Shenling Baizhu oral liquid were added to drinking water,respectively.The experiment period was 42 days.Serum and intestinal tissue samples of broilers were collected and the relevant indexes were detected.The results showed as follows:Compared with blank control group,the average daily gain of low-dose and high-dose groups at 1-42 days of ages were significantly increased(P<0.05),and the ratio of feed to gain was significantly decreased(P<0.05).At 21 days of age,spleen index in low-dose group was significantly increased(P<0.05);The IgA contents in low dose group and high dose group were significantly increased(P<0.05).The villus height and the ratio of villus to crypt in duodenum of low dose group were significantly increased(P<0.05),and crypt depth was significantly decreased(P<0.05).The contents of duodenalα-amylase and jejunal lipase in Astragalus polysaccharide group,low dose group and high dose group were significantly increased(P<0.05);The crude fat and crude protein of Astragalus polysaccharide group,low dose group and high dose group were significantly increased(P<0.05).At 42 days of age,the spleen index of Astragalus polysaccharide group and low-dose group was significantly increased(P<0.05);The contents of IgA and IgG in low dose group and high dose group were significantly increased(P<0.05).The ratio of chorio-crypt in duodenum and jejunum of Astragalus polysaccharide group,low dose group and high dose group was significantly increased(P<0.05),and the crypt depth was significantly decreased(P<0.05).The results showed that Shenling Baizhu oral liquid could improve the growth performance,immunity and intes

关 键 词：参苓白术口服液 肉鸡 生长性能 免疫力 肠道功能 

分 类 号：S831.5[农业科学—畜牧学] S853.7[农业科学—畜牧兽医] S858.31