Clinical Features and Etiology of Recurrent Hypertension after Adrenalectomy  

作　　者：Xilan Dong Qianhui Ling Jin Bian Yuehua Li Mengjia Chen Sufang Hao Wenjun Ma Huimin Zhang Jun Cai Ying Lou 

机构地区：[1]Hypertension Center,FuWai Hospital,State Key Laboratory of Cardiovascular Disease of China,National Center for Cardio-vascular Diseases of China,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China

出　　处：《Cardiovascular Innovations and Applications》2024年第1期152-159,共8页心血管创新与应用(英文)

基　　金：funding agency in the public,commercial,or notforprofit sectors.

摘　　要：Patients who undergo adrenalectomy for unilateral primary aldosteronism(PA)may still develop post-surgery hyper-tension;however,the clinical characteristics and etiology of patients developing recurrent hypertension after adrenal-ectomy are unclear.We analyzed the records of 43 patients with recurrent elevated blood pressure after adrenalectomy,who were treated at our center.Standard routine clinical screening workup was used to identify the cause of recurrent hypertension.Causes of recurrent hypertension after adrenalectomy included essential hypertension,primary aldoster-onism,obstructive sleep apnea,renal artery stenosis,and Takayasu arteritis.Before adrenalectomy,39.5%of patients were diagnosed with confirmed or suspected PA,primarily through CT imaging.Adrenal venous sampling(AVS)tests were not conducted on any patients,and 72.1%patients underwent partial adrenalectomy.Among all patients,elevated blood pressure was observed in 44.2%immediately post-operation,18.6%within 1 month,16.3%in 1–6 months,and 20.9%>6 months after operation.Most patients had hypertension of grade 2 and above.Standard endocrine functional assessment and AVS tests should be performed before adrenalectomy to ensure more accurate diagnosis and favora-ble post-operative outcomes.Additionally,individuals often develop essential hypertension regardless of past adrenal disease.

关 键 词：ADRENALECTOMY HYPERTENSION OUTCOMES primary aldosteronism RECURRENT 

分 类 号：R699.3[医药卫生—泌尿科学] R73[医药卫生—外科学]