Clinical Characteristics and Features of Idiopathic Premature Ventricular Contractions with an Enlarged Left Atrium in Patients Without Structural Heart Diseases  

作　　者：Xue Kuang Yuxiang Long Jinhang Che Caiyin Zheng Zengzhang Liu 

机构地区：[1]Department of Cardiology,The Second Affiliated Hospital/The Second Clinical Institute,Chongqing Medical University,Chongqing,China

出　　处：《Cardiovascular Innovations and Applications》2024年第1期174-181,共8页心血管创新与应用(英文)

摘　　要：Background and aims:Idiopathic premature ventricular contractions(PVCs)may cause subtle changes in left atrium(LA)structure and function.Here,we investigated whether serum sodium,body mass index(BMI),N-terminal pro-B-type natriuretic peptide(NT-proBNP)and other characteristics might be associated with LA in these patients.Methods:A total of 268 consecutive patients diagnosed with idiopathic PVCs were retrospectively analyzed.We assessed associations of enlarged LA and with the clinical features obtained from 24-hour Holter monitoring,electro-cardiography and serum data in patients with PVCs.Results:Patients with an enlarged LA(n=101),compared with a normal LA(n=167),had significantly lower serum sodium(140.9±3.0 mmol/L vs 141.7±2.8 mmol/L;P=0.022),higher BMI(24.5±2.7 kg/m2 vs 21.7±2.5 kg/m2;P<0.001),higher NT-proBNP[99.3(193.6)pg/mL vs 77.8(68.8)pg/mL;P<0.001]and lower average heart rates(73.0±8.0 bpm vs 75.3±7.6 bpm;P=0.019).No significant differences were observed in P-wave dispersion,QRS duration,PVC coupling interval,pleomorphism,circadian rhythm,non-sustained ventricular tachycardia,serum potassium,serum magnesium,hypersensitive C-reactive protein,low-density lipoprotein cholesterol,symptoms and PVC duration.Conclusions:Beyond the burden of PVCs,attributes such as serum sodium,BMI,NT-proBNP and average heart beats may potentially correlate with LA enlargement in individuals with idiopathic PVCs.

关 键 词：premature ventricular contractions left atrium serum sodium body mass index N-terminal pro-B-type natriuretic peptide 

分 类 号：R541.7[医药卫生—心血管疾病]