Comparison of the “Late Catch-Up” Phenomenon Between BuMA Supreme and XIENCE Stents Through Serial Optical Coherence Tomography at 1-2 Month and 2 Year Follow-Ups: A Multicenter Study  

作　　者：Qinhua Jin Jianguo Cui Changqian Wang Bei Shi Xi Su Guosheng Fu Yanqing Wu Qiansu Yang Yundai Chen 

机构地区：[1]The General Hospital of Chinese People’s Liberation Army,Beijing,China [2]Nankai University,Tianjin,China [3]Shanghai 9th People’s Hospital,Shanghai,China [4]Affiliated Hospital of Zunyi Medical College,Guizhou Sheng,China [5]Wuhan Asia Heart Hospital,Wuhan,China [6]Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Zhejiang,China [7]^(nd)Affiliated Hospital of Nanchang University,Nanchang,China

出　　处：《Cardiovascular Innovations and Applications》2024年第1期496-506,共11页心血管创新与应用(英文)

基　　金：funded by SINOMED,Tianjin,China.

摘　　要：Objectives:This study was aimed at comparing the“late catch-up”phenomenon between the BuMA Supreme bioresorbable polymer sirolimus-eluting stent and the XIENCE stent through serial optical coherence tomography(OCT)at within 2 months and 2 year follow-ups.Methods:A total of 49 of 75 patients from the PIONEER-II study were enrolled in a 2 year OCT follow-up study;44 patients with 50 lesions were included in the statistical analysis.The primary endpoints were neointimal thickness and late luminal loss(LLL)after stent implantation.Results:The stenosis diameter,and minimum in-stent or in-segment diameter,did not significantly differ between the BuMA Supreme and XIENCE arms at within 2 months and 2 year follow-ups.The strut neointimal coverage and thickness were greater in the BuMA group than the XIENCE group at the 1 and 2 month follow-ups(P=0.044 and P=0.010,respectively)but not at the 2 year OCT follow-up.Neither early luminal loss at the within 2 months follow-up(P=0.849)nor LLL at the 2 year OCT follow-up(P=0.613)showed differences between device arms.No significant differences in imaging and clinical endpoints were observed between device arms at follow-up.Conclusions:The BuMA Supreme stent’s faster re-endothelization with no“late catch-up”phenomenon has potential advantages over the XIECE stent for patients with coronary artery disease and high bleeding risk because it decreases the duration of dual antiplatelet therapy.

关 键 词：late catch-up late luminal loss optical coherence tomography bioresorbable polymer 

分 类 号：R541.4[医药卫生—心血管疾病]