Five-Year Clinical Outcomes After XIENCE PRIME Everolimus Elution Coronary Stent System(EECSS)Implantation  

作　　者：Rongrong Shen Peiyu Zhang Jing Liu Rong Guo Yawei Xu 

机构地区：[1]Department of Cardiology,Shanghai Tenth People’s Hospital,Tongji University School of Medicine,Shanghai 200072,China [2]The First Affiliated Hospital,Medical School of Shihezi University,Shihezi City,Xinjiang,China [3]Pan-Vascular Research Institute,Heart,Lung,and Blood Center,Tongji University,Shanghai,China

出　　处：《Cardiovascular Innovations and Applications》2023年第1期1-9,共9页心血管创新与应用(英文)

基　　金：This study was supported by grants from Clinical Research Plan of SHDC(SHDC2020CR1040B).

摘　　要：Background/aim:This study was aimed at evaluating 5-year effectiveness and safety in participants after XIENCE PRIME Everolimus Elution Coronary Stent System(EECSS)implantation.Materials and methods:From December 2013 to May 2014,108 patients(127 lesions)were treated with the XIENCE PRIME EECSS.The entire follow-up included annual assessments for 5 years after treatment or until one of the clinical endpoints was reached.We evaluated the 5-year clinical outcomes with Kaplan-Meier analysis and the Cox regression model.Results:Nearly three-quarters of the participants were men(76.8%),and the average age was 65.6±10.8 years.Bifurcation lesions accounted for 96.1%(122 lesions),and left main lesions accounted for 3.9%(five lesions),with a total count of 127 lesions.The cumulative rate of major adverse cardiac events was as follows:1 year,1.9%;2 year,4.0%;and 5 year,10.0%.No definite or probable stent thrombosis was observed,and the rate of target lesion failure was only 3.3%over 5 years.The cumulative rate of major bleeding eventually increased to only 4.4%.Conclusions:The 5-year clinical outcomes were favorable in patients treated with XIENCE PRIME EECSS,and the incidence of stent thrombosis and target lesion failure was relatively low.The incidence of major bleeding gradually increased but remained moderate.

关 键 词：major adverse cardiac events major bleeding events stent thrombosis XIENCE PRIME Everolimus Elution Coronary Stent System 

分 类 号：R541.4[医药卫生—心血管疾病]