Angiography-Derived Fractional Flow Reserve in Coronary Assessment: Current Developments and Future Perspectives  

作　　者：Han Bing Chow Shirley Siang Ning Tan Wei Hong Lai Alan Yean Yip Fong 

机构地区：[1]Faculty of Medicine&Health Sciences,University Malaysia Sarawak,Jalan Datuk Mohammad Musa,Kota Samarahan 94300,Sarawak,Malaysia [2]Sarawak Heart Centre,Kuching-Samarahan Expressway,Kota Samarahan 94300,Sarawak,Malaysia [3]Clinical Research Centre,Institute for Clinical Research,Sarawak General Hospital,Jalan Hospital,Kuching 93586,Sarawak,Malaysia [4]Pharmacy Department,Sarawak General Hospital,Jalan Hospital,Kuching 93586,Sarawak,Malaysia

出　　处：《Cardiovascular Innovations and Applications》2023年第1期79-96,共18页心血管创新与应用(英文)

摘　　要：Coronary physiology assessment is an important factor in guiding myocardial revascularization.A growing body of research highlights the value of using fractional flow reserve,FFR and other pressure-based indicators for functional assessment of stable coronary stenoses.Invasive functional coronary assessment techniques have evolved from intra-coronary wire-based to wire-free approaches as a result of technological advancements.In addition,several soft-ware programs on the market have been thoroughly investigated and validated against invasive FFR,and have shown good accuracy and correlation.However,use of FFR remains modest.Hence,this review provides an overview of angiography-based FFR solutions and compares their technologies.Additionally,a systematic scoping review was performed to understand the research landscape in wire-free coronary physiology assessment,to complement the nar-ratives of existing FFR trials on wire-free FFR.Furthermore,future developments and strategies that could expand the use of wire-free computed coronary functional assessment in the Asia Pacific region are discussed.

关 键 词：Angiography-based FFR wire-free FFR Percutaneous coronary intervention Coronary physiological assessment 

分 类 号：R54[医药卫生—心血管疾病] R541.4[医药卫生—内科学]