HIV感染者继发口咽念珠菌病风险评估量表的编制及信效度检验  

Development of an Assessment Scale of Oropharyngeal Candidiasis Risks in HIV-infected Patients and its test of validity and reliability

作　　者：孙丹萍[1] 王华芬 黄莺[1] 邵丽芳[1] 鲁慧琴 詹晓琴 SUN Danping;WANG Huafen;HUANG Ying;SHAO Lifang;LU Huiqin;ZHAN Xiaoqin

机构地区：[1]浙江大学医学院附属第一医院感染科,杭州市310000 [2]浙江大学医学院附属第一医院护理部,杭州市310000

出　　处：《中华护理杂志》2025年第6期723-728,共6页Chinese Journal of Nursing

基　　金：浙江省医药卫生科技计划项目(2024KY985);浙大一院护理学科建设科研项目(2022ZYHL024)。

摘　　要：目的编制HIV感染者继发口咽念珠菌病风险评估量表并验证其信效度。方法通过文献分析法、德尔菲专家函询法和层次分析法形成量表初稿,采用便利抽样法,选取2023年10月-2024年1月杭州市某三级甲等综合医院收治的231例HIV感染者进行问卷调查,检测量表的信效度。结果该量表包含一般因素、HIV相关因素和口腔相关因素3个维度,12个一级条目和21个二级条目。量表总的Cronbach’sα系数为0.813,内容效度指数为0.98,各维度的相关性为0.574~0.733(P<0.05)。验证性因子分析显示,量表模型适配度各检验量均在可接受范围,模型拟合良好。利用受试者操作特征曲线确定量表的临界值为30.5分,该曲线下面积为0.909,灵敏度和特异度分别为0.962和0.697。结论HIV感染者继发口咽念珠菌病风险评估量表具有良好的信效度,可作为口咽念珠菌病风险有效识别和预测的辅助工具。Objective To develop an assessment scale of oropharyngeal candidiasis risks in HIV-infected patients,and to test its reliability and validity.Methods The draft of the assessment scale was constructed by the literature analysis method,Delphi consultations and analytic hierarchy process.Totally 231 HIV-infected patients in a tertiary A hospital of Hangzhou were recruited for questionnaire survey in October 2023 to January 2024.Results The scale includes 3 dimensions,including general factors,HIV related factors and oral related factors,12 first-level items and 21 second-level items.The Cronbach’sαcoefficient of the scale was 0.813;the content validity index was 0.98;the correlation of each dimension was 0.574~0.733(P<0.05).Confirmatory factor analysis showed that the 3 factor models fitted the data well.The critical value(30.5 points)of the scale was determined by ROC curve;the area under the curve was 0.909;the sensitivity of index system was 0.962,and specificity was 0.697.Conclusion The assessment scale of oropharyngeal candidiasis risks in HIV-infected patients has good reliability and validity,and it can be used as an auxiliary tool for effective identification and prediction of oropharyngeal candidiasis risk.

关 键 词：人类免疫缺陷病毒 念珠菌病 风险评估 量表 信度 效度 护理 

分 类 号：R51[医药卫生—内科学]