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作 者:刘晏铭 孙淑玉 李嵩 武剑[1] LIU Yanming;SUN Shuyu;LI Song;WU Jian(Department of Rheumatology and Immunology,The First Affiliated Hospital of Soochow University,Suzhou 215000,China)
机构地区:[1]苏州大学附属第一医院风湿免疫科,江苏苏州215000
出 处:《内科理论与实践》2024年第6期409-412,共4页Journal of Internal Medicine Concepts & Practice
摘 要:皮肤钙质沉着症(calcinosis cutis)是皮肌炎及系统性硬化症的并发症之一,在其他自身免疫性疾病,尤其是系统性红斑狼疮(systemic lupus erythematosus,SLE)中罕见。本文报道了1例确诊SLE 8年的女性患者出现广泛钙质沉着,主要累及四肢,经加用托法替布治疗后有所改善。SLE合并钙质沉着症患者罕见,其发病机制以及治疗方案仍需更多探索和研究,医师需要对此类患者早发现、早诊断、早治疗。Calcinosis cutis is one of the complications of dermatomyositis and systemic sclerosis,while it is rare in other autoimmune diseases,especially in systemic lupus erythematosus(SLE).This article reports a female patient who had been diagnosed with SLE for 8 years ago,and developed extensive calcification,mainly affecting the limbs.Her condition improved after receiving treatment with tofacitinib.SLE patients complicated with calcinosis are rare,and their pathogenesis and treatment strategies still require doing more exploration and research.Early detection,early diagnosis,and early treatment are essential for the patients.
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