碳酸司维拉姆联合营养干预治疗肾功能衰竭维持性血液透析患者的效果  

Effect of Sevelamer Carbonate Tablets Combined with Nutrition Intervention on Maintenance Hemodialysis Patients with Renal Failure

作　　者：柳亚慧 LIU Yahui(Blood Purification Room,Xiamen Fifth Hospital,Xiamen,Fujian 361101,China)

机构地区：[1]厦门市第五医院血液净化室,福建厦门361101

出　　处：《中国医药指南》2025年第10期48-50,共3页Guide of China Medicine

摘　　要：目的探析碳酸司维拉姆联合营养干预治疗肾功能衰竭维持性血液透析患者的效果与价值。方法样本收录时间:2023年1月至2024年6月,样本收录容量:厦门市第五医院收治60例肾功能衰竭维持性血液透析患者,依据治疗方案不同将纳入患者分入两组,对照组30例予以营养干预,观察组30例采用碳酸司维拉姆联合营养干预治疗,比较两组营养指标、肾功能指标、钙磷代谢水平、并发症发生率。结果治疗后,与对照组比较,观察组总蛋白、白蛋白、前白蛋白、血红蛋白水平均更高(P<0.05)。治疗后,与对照组比较,观察组血尿素氮、血肌酐水平均更低(P<0.05)。治疗后,与对照组比较,观察组血钙更高,血磷、钙磷乘积均更低(P<0.05)。与对照组比较,观察组心血管、血液、呼吸、消化系统并发症总发生率更低(P<0.05)。结论针对肾功能衰竭维持性血液透析患者,予以碳酸司维拉姆联合营养干预治疗,可显著改善患者营养指标、肾功能指标,同时也能更好调节钙磷代谢水平、明显降低并发症发生率。Objective To explore the effect and value of Sevelamium carbonate combined with nutrition intervention in the treatment of renal failure maintenance hemodialysis patients.Methods Sample collection time:January 2023 to June 2024,sample collection capacity:Sixty patients with renal failure maintenance hemodialysis admitted to Xiamen Fifth Hospital were divided into two groups according to different treatment plans,30 patients in the control group received nutritional intervention,and 30 patients in the observation group received combined nutritional intervention with Sevelamium carbonate.The nutritional indexes,renal function indexes,calcium and phosphorus metabolism levels,and complication rate of the two groups were compared.Results After treatment,compared with control group,the levels of total protein,albumin,prealbumin and hemoglobin in observation group were higher(P<0.05).After treatment,serum urea nitrogen and serum creatinine levels in the observation group were lower than those in the control group(P<0.05).After treatment,compared with the control group,the blood calcium in the observation group was higher,and the product of blood phosphorus and calcium phosphorus was lower(P<0.05).Compared with the control group,the total incidence of cardiovascular,blood,respiratory and digestive complications in the observation group was lower(P<0.05).Conclusions For maintenance hemodialysis patients with renal failure,Sevelamer Carbonate Tablets combined with nutritional intervention can significantly improve the nutritional index and renal function index of patients,at the same time,it can better regulate the level of calcium and phosphorus metabolism and significantly reduce the incidence of complications.

关 键 词：肾功能衰竭 维持性血液透析 营养干预 碳酸司维拉姆 营养状况 肾功能 钙磷代谢 

分 类 号：R592.5[医药卫生—老年医学]