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作 者:邓英 张同蕾 梁磊 苏锋 李晓茜 周蓉 范中学 王璐 Deng Ying;Zhang Tonglei;Liang Lei;Su Feng;Li Xiaoqian;Zhou Rong;Fan Zhongxue;Wang Lu(Department for Endemic Disease Control,Ankang Center for Disease Control and Prevention,Ankang 725000,China;Institute for Endemic Disease Control,Shaanxi Center for Disease Control and Prevention,Xi'an 710054,China;Laboratory of Endemic Diseases,Shaanxi Center for Disease Control and Prevention,Xi'an 710054,China)
机构地区:[1]陕西省安康市疾病预防控制中心地方病防制科,安康725000 [2]陕西省疾病预防控治中心地方病预防控制所,西安710054 [3]陕西省疾病预防控制中心地方病检验所,西安710054
出 处:《中华地方病学杂志》2025年第2期137-141,共5页Chinese Journal of Endemiology
摘 要:目的了解陕西省安康市地方性氟骨症(简称氟骨症)患者治疗和管理情况,为氟骨症患者治疗及管理方案的调整、优化提供科学依据。方法回顾性分析自安康市各县级疾病预防预控中心收集到的2019—2023年氟骨症病区患者信息,包括人口学信息,临床治疗及慢性病管理情况,救治台账、工作报告及总结等,了解氟骨症患者的治疗意愿、方法及效果,评价氟骨症患者疾病管理情况。结果2019—2023年安康市有治疗意愿的氟骨症患者占比从2019年的76.80%(1089/1418)上升至2023年的100%(1408/1408),呈逐年上升趋势(χ^(2)趋势=971.15,P<0.001)。实际治疗患者6876例,治疗率为100%,以药物治疗为主(99.64%,6851/6876),有效率为94.90%(6525/6876)。氟骨症患者治疗有效率从2019年的88.71%(966/1418)上升至2023年的94.67%(1333/1408),呈逐年上升趋势(χ^(2)趋势=1002.92,P<0.001)。药物治疗不良反应率为0.36%(25/6876)。口服药物治疗联合局部用药治疗有效率最高(97.62%,3566/3653)。各年度氟骨症患者管理率、签约服务率均为100%,规范管理率均在99%以上。结论安康市氟骨症患者治疗意愿高,治疗效果良好,患者签约服务及管理工作落实到位。未来应持续做好氟骨症患者的防治、管理及健康教育工作。ObjectiveTo investigate the treatment and management of patients with endemic fluorosis(referred to as fluorosis)in Ankang City,Shaanxi Province,and to provide a scientific basis for adjusting and optimizing treatment and management strategies for fluorosis patients.MethodsA retrospective analysis was conducted on patient information collected from county-level disease prevention and control centers in Ankang City from 2019 to 2023.Data included demographic information,clinical treatment,chronic disease management,treatment records,work reports,and summaries.The study aimed to learn about the treatment willingness,methods,and effects of patients with fluorosis,and to evaluate the disease management situation of patients with fluorosis.ResultsFrom 2019 to 2023,the proportion of fluorosis patients who were willing to receive treatment in Ankang City had increased from 76.80%(1089/1418)in 2019 to 100%(1408/1408)in 2023,showing an upward trend year by year(χ^(2) trend=971.15,P<0.001).A total of 6876 patients received treatment,with a treatment rate of 100%.The majority of patients received drug treatment(99.64%,6851/6876),with an effective rate of 94.90%(6525/6876).The effective rate of treatment for patients with fluorosis had increased from 88.71%(966/1418)in 2019 to 94.67%(1333/1408)in 2023,showing an upward trend(χ^(2) trend=1002.92,P<0.001).The adverse reaction rate of drug treatment was 0.36%(25/6876).The combination of oral medication and local treatment had the highest effective rate(97.62%,3566/3653).The management rate and contracted service rate of fluorosis patients were 100%each year,and the standardized management rate was above 99%.ConclusionsFluorosis patients in Ankang City have a high willingness to receive treatment,with good treatment outcomes.The contracted services and management of patients are well implemented.In the future,continuous efforts should be made to improve the prevention,management,and health education of fluorosis patients.
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