cfDNA在感染性疾病诊断中的研究进展  

The Research Progress of cfDNA in the Diagnosis of Infectious Diseases

作　　者：陈颖琦 胥萍[1,2] CHEN Yingqi;XU Ping(Suzhou Medical College of Soochow University,Suzhou 215131,China;Department of ClinicalLaboratory,the Affiliated Infectious Diseases Hospital of Soochow University,Suzhou 215131,China)

机构地区：[1]苏州大学苏州医学院,江苏苏州215131 [2]苏州大学附属传染病医院检验中心,江苏苏州215131

出　　处：《标记免疫分析与临床》2025年第2期424-429,共6页Labeled Immunoassays and Clinical Medicine

基　　金：苏州市基础研究计划-医学应用基础研究[人乳头瘤病毒(HPV)感染全周期健康监测及诊断新技术和新方法的研究](编号:SKY2023073);江苏省科学技术厅-重点研发计划社会发展(单细胞免疫功能表征在结核感染时序分析中的诊断价值及临床应用)(编号:BE2023718)。

摘　　要：感染性疾病是由致病微生物(包括细菌、病毒、寄生虫等)侵入感染而引起的疾病,近年研究表明,cfDNA(cell-free DNA)作为一种新型生物检测标志物,有助于识别多种来源和部位的感染,为感染性疾病诊断实践提供新思路。本文总结了利用cfDNA在感染性疾病诊断中的一系列文献,以期为今后感染性疾病尽早准确诊断研究提供参考和借鉴。Infectious diseases are caused by the invasion of pathogenic microorganisms(including bacteria,viruses,parasites,etc.).Recent studies have shown that cell-free DNA(cfDNA),as a new bio-detection marker,can help to identify the infection of various sources and sites,which provides novel insights for the diagnosis of infectious diseases.This paper summarizes a series of literatures using cfDNA in the diagnosis of infectious diseases,aiming to provide valuable references for the early and accurate diagnosis of infectious diseases in the future.

关 键 词：cfDNA 感染性疾病 诊断 研究 

分 类 号：R51[医药卫生—内科学]