云南省贡山县少数民族高尿酸血症患病率调查  

A Survey on the Prevalence of Hyperuricemia among Ethnic Minorities in Gongshan County,Yunnan Province

作　　者：沈亚洁 杨亚丽 余志清 乔诚 SHEN Yajie;YANG Yali;YU Zhiqing;QIAO Cheng(Department of Nephrology,Gongshan County People's Hospital,Nujiang Prefecture,Nujiang Yunnan 673500;Department of Nephrology,Zhoupu Hospital Affiliated to Shanghai Medical College of Health,Shanghai 201318,China)

机构地区：[1]贡山县人民医院肾内科,云南怒江673500 [2]上海健康医学院附属周浦医院肾内科,上海201318

出　　处：《昆明医科大学学报》2025年第3期39-43,共5页Journal of Kunming Medical University

基　　金：浦东新区卫生系统优秀青年医学人才培养计划(PWRq2022-18);上海健康医学院校级科研基金资助项目(SSF-23-17-004);上海健康医学院附属周浦医院2023年度院级人才项目(ZPRC-2023A-14)。

摘　　要：目的通过横断面调查研究云南省贡山县少数民族群体高尿酸血症患病率情况。方法在云南省贡山县随机选取独龙族、怒族、藏族、白族、傈僳族等≥18岁居民共229人进行问卷调查、体格检查和实验室检测。采用SPSS 22.0进行t检验、卡方检验、相关性分析和多因素Logistic回归分析。结果共检出高尿酸血症患者107例,检出率为46.7%,其中男性为43.9%、女性为52.63%;独龙族48%,傈僳族51%,怒族47%,白族37.5%,藏族52%,汉族50%,各民族间患病率差异无统计学意义(P>0.05)。高尿酸血症组人群组糖尿病史占比和尿素氮、血肌酐水平明显高于非高尿酸血症组(P<0.05),相关性分析显示高尿酸血症与糖尿病、尿素氮、血肌酐呈正相关(P<0.05),多因素回归分析显示,糖尿病、血肌酐升高,是高尿酸血症发病的独立高危因素(P<0.05)。结论云南省贡山县高尿酸血症检出率较高,各少数民族之间高尿酸血症患病率无明显差异,糖尿病、血肌酐升高与高尿酸血症存在关联性,同时也会增加高尿酸血症发生的风险。Objective To investigate the prevalence of hyperuricemia among ethnic groups in Gongshan county,Yunnan province through a cross-sectional study.Methods A total of 229 residents aged≥18 years from Dulong,Nu,Tibetan,Bai and Lisu ethnic groups were randomly selected in Gongshan County of Yunnan Province for questionnaire survey,physical examinations and laboratory tests.SPSS 22.0 was used for t test,Chi-square test,correlation analysis,and multivariate logistic regression analysis.Results A total of 107 cases of hyperuricemia were identified,with a detection rate of 46.7%,among which the prevalence was 43.9%in males,52.63%in female,48%in the Dulong,51%in the Lisu,47%in the Nu,37.5%in the Bai,52%in the Tibetan and 50%in the Han.There were no statistically significant differences in prevalence among all nationalities(P>0.05).The proportion of individuals with a history of diabetes,as well as levels of urea nitrogen and serum creatinine,were significantly higher in the hyperuricemia group compared to the non-hyperuricemia group(P<0.05).Correlation analysis showed a positive correlation between hyperuricemia and diabetes,urea nitrogen and serum creatinine.(P<0.05).Multivariate regression analysis showed that diabetes and elevated serum creatinine were independent risk factors for the onset of hyperuricemia(P<0.05).Conclusion The detection rate of hyperuricemia is relatively high in Gongshan County,Yunnan Province,and there is no significant differences in prevalence among ethnic groups.Diabetes and elevated serum creatinine are associated with hyperuricemia,which increase the risk of developing hyperuricemia.

关 键 词：高尿酸血症 贡山县 独龙族 怒族 

分 类 号：R589.7[医药卫生—内分泌]