壳聚糖基水凝胶的构建及在抗菌医用敷料中的应用  

Construction of chitosan-based hydrogel and its application in antibacterial medical dressings

作　　者：孙筱 刘玉[1] 张群 孙洋洋 SUN Xiao;LIU Yu;ZHANG Qun;SUN Yang-yang(State Key Laboratory of Green Papermaking and Resource Recycling,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250300,China)

机构地区：[1]齐鲁工业大学(山东省科学院)绿色造纸与资源循环全国重点实验室,山东济南250300

出　　处：《现代化工》2025年第4期54-57,63,共5页Modern Chemical Industry

基　　金：国家自然科学基金面上项目(32171718);齐鲁工业大学(山东省科学院)人才科研项目(2023RCKY207);齐鲁工业大学(山东省科学院)科教产融合试点工程基础研究类项目(2023PX107)。

摘　　要：系统地介绍了几种具有代表性的壳聚糖水凝胶,包括负载抗生素壳聚糖水凝胶、负载活性物质壳聚糖水凝胶和含金属基无抗生素壳聚糖水凝胶,还对壳聚糖水凝胶在生物医学应用中的局限性和未来发展做了简明的评估。Several kinds of representative chitosan-based hydrogel are introduced systematically,including antibiotics-loading chitosan-based hydrogel,active substances-loading chitosan-based hydrogel and metals-containing antibiotics-free chitosan-based hydrogel.The research progress on chitosan-based hydrogel as antibacterial medical dressings in recent years is reviewed,including preparation methods,antibacterial mechanism and antibacterial properties.Additionally,the current limitations and future development of chitosan-based hydrogel are briefly evaluated.

关 键 词：壳聚糖 水凝胶 抗菌材料 生物医学 

分 类 号：TH3[机械工程—机械制造及自动化]