基于“心-肾-骨”轴论治围绝经期骨质疏松  

Treatment of Perimenopausal Osteoporosis Based on the“Heart-Kidney-Bone”Axis

作　　者：韩化伟 王欣哲 金杰 陈帅 田宁晟 李志伟[1] HAN Huawei;WANG Xinzhe;JIN Jie;CHEN Shuai;TIAN Ningsheng;LI Zhiwei(Department of Orthopedics,The Second Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210017,China;Department of Gynecology,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China)

机构地区：[1]南京中医药大学第二附属医院骨伤科,江苏南京210017 [2]南京中医药大学附属医院妇科,江苏南京210029

出　　处：《山东中医杂志》2025年第4期396-400,共5页Shandong Journal of Traditional Chinese Medicine

基　　金：江苏省科技计划专项资金(重点研发计划社会发展)项目(编号:BE2023787);江苏省卫生健康委员会老年健康科研项目(编号:LKZ2022008);南京中医药大学第二附属医院(江苏省第二中医院)基金项目(编号:SEZYB2023004);江苏省研究生科研与实践创新计划项目(编号:SJCX24_1019)。

摘　　要：随着中国社会老龄化进程,围绝经期骨质疏松的防治日益得到重视。本文基于心、肾、骨之间的联系,创新性提出“心-肾-骨”轴概念,并以此为基础分别从中医和西医角度探讨了围绝经期骨质疏松的发病机制:西医学视角下,可用神经-内分泌共病解释;中医病机则可归纳为以肾虚为本的心肾不交。故治疗上应以补肾调心为要领,治以补肾益髓、交通心肾。With the aging process of Chinese society,the prevention and treatment of perimenopausal osteoporosis have increasingly gained attention.Based on the interconnection among the heart,kidney and bone,this paper innovatively proposes the concept of the“heart-kidney-bone”axis,and the pathogenesis of perimenopausal osteoporosis is discussed from the perspective of traditional Chinese and western medicine on this basis:From the perspective of western medicine,it can be explained by neuroendocrine comorbidity;The pathogenesis of traditional Chinese medicine can be summarized as disharmony between the heart and kidney rooted in kidney deficiency.Therefore,the treatment should focus on tonifying the kidney and regulating the heart,with therapeutic principles of tonifying kidney and replenishing marrow,communicating the heart and the kidney.

关 键 词：“心-肾-骨”轴 围绝经期骨质疏松 补肾益髓 交通心肾 神经-内分泌共病 

分 类 号：R259[医药卫生—中西医结合] R271.116[医药卫生—中医内科学]