基于离散选择实验的胃癌患者治疗偏好研究  

Study on Treatment Preference of Gastric Cancer Patients based on Discrete Choice Experiments

作　　者：贾宇衡 杨毅 洪立信[4] 张芃 田侃 王志刚[7] JIA Yuheng;YANG Yi;HONG Lixin;ZHANG Peng;TIAN Kan;WANG Zhigang(School of Health Economics and Management,Nanjing University of Chinese Medicine,Nanjing Jiangsu 210023,China;不详)

机构地区：[1]南京中医药大学卫生经济管理学院,江苏南京210023 [2]复旦大学公共卫生学院,上海200032 [3]国家卫生健康委员会卫生技术评估重点实验室(复旦大学),上海200032 [4]南京中医药大学药学院,江苏南京210023 [5]上海应用技术大学人文学院,上海201418 [6]南京中医药大学养老服务与管理学院,江苏南京210023 [7]江苏省肿瘤医院,江苏南京210009

出　　处：《卫生经济研究》2025年第4期28-32,共5页

基　　金：国家自然科学基金“基于多模态融合数据的肿瘤低价值医疗服务利用行为研究:评价工具、驱动机制及防范策略”(72404060);国家卫生健康委员会卫生技术评估重点实验室(复旦大学)开放基金课题“消化道肿瘤的疾病经济负担及患者治疗偏好研究”(FHTA2023-03)。

摘　　要：目的:研究胃癌患者治疗偏好的属性及水平,为胃癌患者治疗决策提供参考依据。方法:通过文献回顾,初步拟定胃癌患者治疗偏好的属性及水平;经过专家咨询及关键知情人访谈,确定属性及水平。结果:最终保留6个胃癌治疗偏好属性,分别为无进展(病)生存期、生命质量、给药频率、肿瘤相关症状、严重治疗副作用(>3级)发生率、每月自付费用。结论:预实验显示,开发得到的胃癌患者治疗偏好的离散选择实验属性及相应水平符合实际且易于理解,可以为医患共同决策提供询证依据。Objective To study the attributes and levels of treatment preferences of gastric cancer patients,and to provide a reference basis for treatment decision-making of gastric cancer patients.Methods The attributes and levels of treatment preferences of gastric cancer patients were initially formulated through literature review.The attributes and levels were determined after expert consultation and key informant interviews.Results 6 most concerned attributes of treatment preferences of gastric cancer patients were finally retained,which were progression-free survival,quality of life,frequency of drug administration,tumor-related symptoms,incidence of serious treatment side effect(>grade 3),and monthly out-of-pocket costs.Conclusion The pre-experiment showed that the developed discrete choice experiment attributes and corresponding levels of treatment preferences of gastric cancer patients were realistic and easy to understand,which could provide an evidence-based basis for joint decision-making between doctors and patients.

关 键 词：离散选择实验 胃癌患者 治疗偏好 

分 类 号：R19[医药卫生—卫生事业管理]