高蛋白饮食对肥胖伴代谢性疾病干预效果及影响的研究进展  

Research progress on the intervention effect and influence of high protein diet on obesity and metabolic diseases

作　　者：刘丹[1,2] 陈静 梁清月[3] LIU Dan;CHENG Jing;LIANG Qingyue(Health Management Center of West China Second Hospital,Chengdu 610066,Sichuan Province,China;Chengdu Tianfu New District Hepin Renji Physical Examination Co.,LTD,Chengdu 610213,Sichuan Province,China;Department of Nutrition,Chengdu Seventh People's Hospital,Chengdu 610299,Sichuan Province,China)

机构地区：[1]四川大学华西第二医院健康管理中心,成都610066 [2]成都天府新区禾品仁济体检有限公司,成都610213 [3]成都市第七人民医院营养科,成都610299

出　　处：《预防医学情报杂志》2025年第3期417-424,共8页Journal of Preventive Medicine Information

摘　　要：超重和肥胖与多种慢性代谢性疾病及死亡风险密切相关,高蛋白饮食在短期内能快速减重,并且在2型糖尿病、血脂代谢异常、高血压、脂肪肝及代谢综合征等相关代谢性疾病的干预具有显著的治疗效果。高蛋白饮食短期内可以明显降低血脂、血压水平,减少血糖波动,以及能够提高机体胰岛素的敏感性,逆转脂肪肝,改善代谢综合征;但长期高蛋白饮食可能会增加胰腺负担,导致糖代谢异常发生,以及增加潜在的心血管疾病发病风险,特别是对于肥胖合并肾功能不全或2型糖尿病的患者,高蛋白饮食可能会加重肾脏损害,不推荐长期使用。Overweight and obesity are closely related to a variety of chronic metabolic diseases and the risk of death.High-protein diet can rapidly lose weight in a short period of time,and it has significant therapeutic effect on the intervention of type 2 diabetes,dyslipidemia,hypertension,fatty liver,metabolic syndrome and other related metabolic diseases.In the short term,high-protein diet can significantly reduce blood lipid and blood pressure levels,reduce blood sugar fluctuations,improve insulin sensitivity,reverse fatty liver and improve metabolic syndrome.However,long-term high-protein diet may increase the burden on the pancreas,lead to abnormal glucose metabolism and increase the potential risk of cardiovascular disease,especially for obese patients with renal insufficiency or type 2 diabetes,high-protein diet may aggravate kidney damage,and long-term use is not recommended.

关 键 词：代谢性疾病 高蛋白饮食 肥胖 效果 

分 类 号：R589[医药卫生—内分泌]