超声引导下穿刺活检术、术中快速冰冻组织活检对乳腺肿块性质的诊断价值比较  

Comparison on the Diagnostic Value of Ultrasound-Guided Biopsy and Intraoperative Rapid Frozen Tissue Biopsy for Nature of Breast Mass

作　　者：师晨阳 高丽 李清苗[1] 段奇 SHI Chenyang;GAO Li;LI Qingmiao;DUAN Qi(Department of Pathology,Nanyang Central Hospital,Nanyang 473000,China)

机构地区：[1]南阳市中心医院病理科,河南南阳473000

出　　处：《临床医学工程》2025年第3期265-268,共4页Clinical Medicine & Engineering

基　　金：河南省医学科技攻关计划联合共建项目(项目编号:LHGJ20191451)。

摘　　要：目的 比较超声引导下穿刺活检术(UGB)、术中快速冰冻组织活检诊断乳腺肿块性质的价值。方法 选取我院2022年3月至2024年2月收治的86例乳腺肿块患者,均进行UGB和术中快速冰冻组织活检,分析二者对乳腺肿块性质的诊断结果、诊断效能、预测值。结果 86例乳腺肿块患者中,术后石蜡病理结果显示阳性48例,阴性38例;UGB检查显示阳性39例,阴性47例;术中快速冰冻组织活检显示阳性46例,阴性40例。UGB检查的敏感性、准确性分别为75.00%、 82.56%,低于术中快速冰冻组织活检的91.67%、 93.02%(P <0.05);UGB检查的漏诊率为25.00%,高于术中快速冰冻组织活检的8.33%(P <0.05)。UGB和术中快速冰冻组织活检的特异性、误诊率、阳性预测值、阴性预测值对比,差异均无统计学意义(P>0.05)。结论 与UGB检查相比,术中快速冰冻组织活检诊断乳腺肿块性质的效能较好,能提高诊断敏感性和准确性,减少漏诊。Objective To compare the value of ultrasound-guided biopsy(UGB)and intraoperative rapid frozen tissue biopsy in the diagnosis of nature of breast mass.Methods 86 patients with breast mass admitted to our hospital from March 2022 to February 2024 were selected.All cases received UGB and intraoperative rapid frozen tissue biopsy.The diagnostic results,diagnostic efficacy and predictive value of the two methods for the nature of breast masses were analyzed.Results Among 86 patients with breast mass,postoperative paraffin pathology results showed 48 positive cases and 38 negative cases;UGB examination showed 39 positive cases and 47 negative cases;Intraoperative rapid frozen tissue biopsy showed 46 positive cases and 40 negative cases.The sensitivity and accuracy of UGB examination were 75.00%and 82.56%,respectively,lower than 91.67%and 93.02%of intraoperative rapid frozen tissue biopsy(P<0.05);The missed diagnosis rate of UGB examination was 25.00%,higher than 8.33%of intraoperative rapid frozen tissue biopsy(P<0.05).No significant difference was found in the specificity,misdiagnosis rate,positive predictive value,and negative predictive value between UGB and intraoperative rapid frozen tissue biopsy(P>0.05).Conclusions Compared with UGB examination,intraoperative rapid frozen tissue biopsy has better efficacy in diagnosing the nature of breast mass,which can improve diagnostic sensitivity and accuracy,and reduce missed diagnosis.

关 键 词：乳腺肿块 超声引导下穿刺活检术 术中快速冰冻组织活检 诊断效能 

分 类 号：R446.8[医药卫生—诊断学]