二尖瓣置换术史孕妇发生感染性心内膜炎致脾梗死1例并文献复习  

One case of splenic infarction due to infective endocarditis in a pregnant woman with history of mitral valve replacement and literature review

作　　者：曹奔奔 CAO Benben(Department of Obstetrics,the First Affiliated Hospital,Zhejiang University School of Medicine,Zhejiang Province,Hangzhou 311100,China)

机构地区：[1]浙江大学医学院附属第一医院产科,浙江杭州311100

出　　处：《妇儿健康导刊》2025年第6期95-98,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

摘　　要：妊娠期感染性心内膜炎(IE)治疗难度较大,尤其对有机械二尖瓣置换术史的孕妇。本文报告1例曾因风湿性心脏病接受二尖瓣置换术治疗,在孕晚期发生IE并继发脾梗死的33岁孕妇,患者既往长期接受抗凝治疗,故临床需要多学科共同管理,该患者最终因胎膜早破进行剖宫产手术。本文旨在为妊娠期IE患者制订个性化治疗策略和多学科团队紧密合作提供参考。Infective endocarditis(IE) during pregnancy poses significant therapeutic challenges,particularly in patients with a history of mechanical mitral valve replacement.This article reports a case of a 33-year-old pregnant woman who had been treated with mitral valve replacement for rheumatic heart disease and developed IE with secondary splenic infarction in late pregnancy.The patient had a long history of anticoagulation therapy,so the clinic required multidisciplinary management,and the patient eventually underwent a cesarean section for premature rupture of membranes.This case report aims to provide insights into the development of personalized treatment strategies and highlight the importance of close collaboration among multidisciplinary teams for managing IE in pregnant patients.

关 键 词：妊娠 二尖瓣置换术 感染性心内膜炎 脾梗死 抗凝治疗 

分 类 号：R714[医药卫生—妇产科学]