海马神经网络异常在脓毒症相关性脑病中的研究进展  

Recent advance in hippocampal neural network abnormalities in sepsis-associated encephalopathy

作　　者：沈埝萱 纪木火 夏德国 Shen Nianxuan;Ji Muhuo;Xia Deguo(Medical College,Yangzhou University,Yangzhou 225000,China;Department of Anesthesiology,Second Affiliated Hospital of Nanjing Medical University,Nanjing 210000,China;Department of Anesthesiology,Northern Jiangsu People's Hospital Affiliated to Yangzhou University,Yangzhou 225000,China)

机构地区：[1]扬州大学医学院,扬州225000 [2]南京医科大学第二附属医院麻醉科,南京210000 [3]扬州大学附属苏北人民医院麻醉科,扬州225000

出　　处：《中华神经医学杂志》2025年第3期317-320,共4页Chinese Journal of Neuromedicine

基　　金：国家自然科学基金面上项目(82372182)。

摘　　要：脓毒症相关性脑病(SAE)是脓毒症累及中枢神经系统所导致的一种弥漫性脑功能障碍,主要临床表现为意识改变及认知功能障碍。海马作为机体认知功能的关键脑区,其神经网络异常与SAE的发生发展密切相关。本文围绕海马神经网络异常在SAE中的研究进展进行综述,以期为临床上SAE的治疗提供新思路。Sepsis-associated encephalopathy(SAE)is a diffuse brain dysfunction caused by sepsis involving the central nervous system,with main clinical manifestations as altered consciousness and cognitive impairment.As a crucial brain region for cognitive function,the hippocampus is closely associated with SAE development through abnormal neural networks.This article reviews the research progress on hippocampal neural network abnormalities in SAE,aiming to provide new ideas for clinical treatment of SAE.

关 键 词：脓毒症 脓毒症相关性脑病 海马 神经网络 神经元 神经振荡 神经环路 

分 类 号：R459.7[医药卫生—急诊医学]