针灸治疗糖尿病胃轻瘫相关机制研究进展  

Progress in the study of mechanisms related to the treatment of diabetic gastroparesis with acupuncture and moxibustion

作　　者：张敏[1] 隋蕙嬬 石宏 薛海波[1] 史宁[1] ZHANG Min;SUI Huiru;SHI Hong;XUE Haibo;SHI Ning(Department of Gastroenterology,Binzhou Medical University Hospital,Shandong,Binzhou 256603,China)

机构地区：[1]滨州医学院附属医院消化内科,山东滨州256603

出　　处：《中国医药科学》2025年第5期29-32,共4页China Medicine And Pharmacy

基　　金：中国疾病预防控制中心公共卫生领域卫生健康标准评估项目(2023-958-5)。

摘　　要：糖尿病胃轻瘫是糖尿病常见的消化道慢性并发症,是以胃动力下降、胃排空延迟、胃节律紊乱等为主要特点,但无机械性梗阻的一组综合征。患者餐后会出现饱腹、恶心、呕吐、腹胀和腹痛等症状,严重影响患者生活质量。随着生活水平的提高,糖尿病患病人数呈增长趋势,糖尿病胃轻瘫的发病率也逐步增加。针灸疗法可改善胃动力和临床症状,效果显著且副作用小。针灸对糖尿病胃轻瘫的治疗与多种机制密切相关,包括调节Cajal间质细胞、促进肠神经系统及自主神经系统恢复、纠正胃肠激素和肠道菌群紊乱、调控胃平滑肌运动、减少氧化应激、改善高血糖状态等。现将针灸(包括针刺、电针、艾灸等)治疗糖尿病胃轻瘫的相关机制进行总结,为今后相关研究提供参考。Diabetic gastroparesis is a common chronic complication of diabetes mellitus in the gastrointestinal tract,which is a group of syndromes characterized by decreased gastric motility,delayed gastric emptying and gastric dysrhythmia,but without mechanical obstruction.Patients will experience symptoms such as postprandial satiety,nausea,vomiting,abdominal distension and abdominal pain,which seriously affect their quality of life.With the improvement of living standards,the number of patients with diabetes mellitus are on the rise,and the incidence of diabetic gastroparesis is gradually increasing.Acupuncture and moxibustion therapies can improve gastric motility and clinical symptoms with significant effects and few side effects.The treatment of diabetic gastroparesis with acupuncture and moxibustion is closely related to multiple mechanisms,including regulation of interstitial cells of Cajal,promotion of enteric nervous system and autonomic nervous system recovery,correction of gastrointestinal hormone and intestinal flora disorders,modulation of gastric smooth muscle motility,reduction of oxidative stress,improvement of hyperglycemic state,etc.Mechanisms related to the treatment of diabetic gastroparesis with acupuncture and moxibustion(including acupuncture,electroacupuncture,moxibustion,etc.)are summarized to provide reference for future studies.

关 键 词：糖尿病 胃轻瘫 针灸 机制 

分 类 号：R246.1[医药卫生—针灸推拿学]