4D数字化弱视斜视矫治系统辅助治疗对屈光参差性弱视患儿视网膜微血流状态及RNFL厚度的影响  

Influence of Adjuvant Therapy of 4D Digital Strabismus and Amblyopia Visual Function Correction System on Retinal Microcirculation and RNFL Thickness in Children with Anisometropic Amblyopia

作　　者：周荣妹 陈群[2] 刘畅 ZHOU Rongmei(EYE&ENT Hospital of Fudan University,Shanghai 200031,China)

机构地区：[1]复旦大学附属眼耳鼻喉科医院眼科,上海200031 [2]上海市浦东新区公利医院眼科,上海200135

出　　处：《河北医学》2025年第3期435-439,共5页Hebei Medicine

基　　金：国家自然科学基金委员会资助项目,(编号:81800851)。

摘　　要：目的:对比4D数字化弱视斜视矫治系统辅助治疗对屈光参差性弱视患儿视网膜微血流状态及视盘周围视网膜神经纤维层(RNFL)厚度的影响。方法:将本院2022年3月至2024年5月收治的118例屈光参差性弱视患儿随机分为对照组(n=59,常规疗法)和治疗组(n=59,4D数字化弱视斜视矫治系统辅助治疗+常规疗法)。评价两组的临床疗效,对比两组治疗前后的视网膜微血流状态、RNFL厚度变化,评价两组治疗前后的立体视异常情况。结果:治疗组的总有效率优于对照组(P<0.05);治疗后治疗组的浅层视网膜毛细血管丛血流密度(SCP)、深层视网膜毛细血管丛血流密度(DCP)、视盘血流密度相较于对照组升高(P<0.05);相较于对照组,治疗组治疗前后的视盘周围各区域(鼻侧、上方、下方)RNFL厚度差值明显增加(P<0.05);治疗后,治疗组的立体视力异常患者立体视力转正常率高于对照组(P<0.05)。结论:对屈光参差性弱视患儿应用4D数字化弱视斜视矫治系统辅助治疗疗效明显,与常规疗法比较,可有效改善患儿的视网膜微血流状态、RNFL厚度及视功能。Objective:To compare the influence of adjuvant therapy of 4D digital strabismus and amblyopia visual function correction system(4D-DSAAVFCS)on retinal microcirculation and retinal nerve fiber layer(RNFL)thickness in children with anisometropic amblyopia(AA).Methods:Totally 118 children with AA in the hospital from March 2022 to May 2024 were randomly divided into control group(n=59,conventional therapy)and treatment group(n=59,4D-DSAAVFCS adjuvant therapy+conventional therapy).The clinical efficacy of the two groups was evaluated.The retinal microcirculation and RNFL thickness before and after treatment were compared between groups,and the rate of stereoscopic acuity converting to normal was evaluated in both groups before and after treatment.Results:The total effective rate in the treatment group was better than that of the control group(P<0.05).Compared with the control group,the blood flow density in superficial capillary plexus(SCP),deep capillary plexus(DCP),and optic blood flow density were significantly increased in the treatment group after treatment(P<0.05).The differences in RNFL thickness of various areas around the optic disc(OD)(nasal,upper and lower)in the treatment group were significantly increased after treatment compared to the control group(P<0.05).After treatment,the rate of stereoscopic acuity converting to normal in patients with abnormal stereoscopic acuity in the treatment group was significantly higher than that of the control group(P<0.05).Conclusion:The adjuvant therapy of 4D-DSAAVFCS has a better efficacy in the treatment of children with AA,and it can more effectively improve the retinal microcirculation,RNFL thickness and visual function of the children compared to conventional therapy.

关 键 词：屈光参差性弱视 4D数字化 弱视斜视矫治系统 视网膜微血流状态 视盘周围视网膜神经纤维层 

分 类 号：R47[医药卫生—护理学]