儿童清肺口服液联合硫酸特布他林雾化吸入治疗急性上呼吸道感染患儿的效果  

Effects of children’s Qingfei oral liquid combined with Terbutaline sulfate aerosol therapy in treatment of children with acute upper respiratory tract infection

作　　者：张浩 牛宛柯 赵蕊 ZHANG Hao;NIU Wanke;ZHAO Rui(Department of Pediatrics of Nanyang Zhangzhongjing Hospital,Nanyang 473000 Henan,China)

机构地区：[1]南阳张仲景医院儿科,河南南阳473000

出　　处：《中国民康医学》2025年第7期37-39,43,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察儿童清肺口服液联合硫酸特布他林雾化吸入治疗急性上呼吸道感染患儿的效果。方法:选取2020年1月至2023年1月该院收治的112例急性上呼吸道感染患儿进行前瞻性研究,按随机数字表法将其分为对照组与研究组各56例。对照组采用硫酸特布他林雾化吸入用溶液雾化吸入治疗,研究组在对照组基础上联合儿童清肺口服液治疗,比较两组临床疗效,治疗前后中医证候积分、炎性因子[白细胞介素(IL)-8、IL-6、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)]水平,以及不良反应发生率。结果:研究组治疗总有效率为96.43%(54/56),高于对照组的83.93%(47/56),差异有统计学意义(P<0.05);治疗后,两组发热、恶风、流浊涕、鼻塞、咳嗽、咽红肿痛等中医证候积分均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);两组IL-8、IL-6、CRP、TNF-α水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:儿童清肺口服液联合硫酸特布他林雾化吸入治疗急性上呼吸道感染患儿可提高治疗总有效率,以及降低中医证候积分和炎性因子水平的效果优于单纯硫酸特布他林雾化。Objective:To observe effects of children’s Qingfei oral liquid combined with Terbutaline sulfate aerosol therapy in treatment of children with acute upper respiratory tract infection.Methods:A prospective study was conducted on 112 children with acute upper respiratory tract infection admitted to the hospital from January 2020 to January 2023.According to the random number table method,they were divided into control group and study group,56 cases in each group.The control group was treated with Terbutaline sulfate inhalation aerosol for aerosol therapy,while the study group was treated with children’s Qingfei oral liquid on the basis of that of the control group.The clinical efficacies,the TCM syndrome scores,the levels of inflammatory factors[interleukin(IL)-8,IL-6,C-reactive protein(CRP),tumor necrosis factor-α(TNF-α)]before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was 96.43%(54/56),which was higher than 83.93%(47/56)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of TCM syndromes such as fever,aversion to wind,runny nose,nasal congestion,cough,pharyngeal swelling and pain in the two groups were lower than those before the treatment,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The levels of IL-8,IL-6,CRP and TNF-αin the two groups were lower than those before the treatment,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Children’s Qingfei oral liquid combined with Terbutaline sulfate aerosol therapy in the treatment of the children with acute upper respiratory tract infection can improve the total effective rate of treatment,and reduce the

关 键 词：急性上呼吸道感染 儿童清肺口服液 硫酸特布他林 雾化吸入治疗 中医证候积分 炎性因子 不良反应 

分 类 号：R725.6[医药卫生—儿科]