Low-dimensional antimicrobial nanomaterials in anti-infection treatment and wound healing  

作　　者：Yunfen Gao Liying Wang Chufan Zhou Yi Zhao Hai Huang Jun Wu 

机构地区：[1]School of Biomedical Engineering,Shenzhen Campus of Sun Yat-sen University,Shenzhen 518107,China [2]Department of Hematology,The Seventh Affiliated Hospital,Sun Yat-sen University,Shenzhen 518107,China [3]School of Life Sciences and Bio-pharmaceutics,Guangdong Pharmaceutics University,Guangzhou 510006,China [4]Department of Urology,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,China [5]Bioscience and Biomedical Engineering Thrust,The Hong Kong University of Science and Technology(Guangzhou),Nansha,Guangzhou 511400,China [6]Division of Life Science,The Hong Kong University of Science and Technology,Hong Kong SAR 999077,China

出　　处：《Chinese Chemical Letters》2025年第3期95-103,共9页中国化学快报(英文版)

基　　金：financially supportsed by National Natural Science Foundation of China(No.52173150);Guangzhou Science and Technology Program City-University Joint Funding Project(No.2023A03J0001);Postdoctoral Science Foundation(No.2022M723670).

摘　　要：Bacterial infections have always been a major threat to human health.Skin wounds are frequently exposed to the external environment,and they may become contaminated by bacteria derived from the surrounding skin,the local environment,and the patient’s own endogenous sources.Contaminated wounds may enter a state of chronic inflammation that impedes healing.Urgent development of antibacterial wound dressings capable of effectively combating bacteria and overcoming resistance is necessary.Nanotechnology and nanomaterials present promising potential as innovative strategies for antimicrobial wound dressings,owing to their robust antibacterial characteristics and the inherent advantage of avoiding antibiotic resistance.Therefore,this review provides a concise overview of the antimicrobial mechanisms exhibited by low-dimensional nanomaterials.It further categorizes common low-dimensional antimicrobial nanomaterials into zero-dimensional(0D),one-dimensional(1D)and two-dimensional(2D)nanomaterials based on their structural characteristics,and gives a detailed compendium of the latest research advances and applications of different low-dimensional antimicrobial nanomaterials in wound healing,which could be helpful for the development of more effective wound dressings.

关 键 词：Nano-antimicrobial materials Antimicrobial mechanisms LOW-DIMENSIONAL Anti-infection treatment Wound healing 

分 类 号：R318.08[医药卫生—生物医学工程]