子宫肌瘤患者行腹腔镜下子宫全切术治疗的预后分析  

Prognostic Analysis of Laparoscopic Total Hysterectomy in Patients with Uterine Fibroids

作　　者：陈香琨 周天兰 王玲 CHEN Xiangkun;ZHOU Tianlan;WANG Ling(Department of Gynecology and Obstetrics,Jiangdu District Maternal and Child Health Hospital,Jiangdu,Jiangsu,225200,China)

机构地区：[1]江都区妇幼保健院妇产科,江苏江都225200

出　　处：《中外医疗》2025年第1期35-38,43,共5页China & Foreign Medical Treatment

摘　　要：目的分析子宫肌瘤患者行腹腔镜下子宫全切术治疗的预后。方法回顾性选取2022年1月至2024年4月江都区妇幼保健院收治的78例子宫肌瘤患者的临床资料,以不同治疗方案分组,即接受传统开腹子宫切除术者为对照组(n=37)、接受腹腔镜下子宫全切术者为观察组(n=41)。对比两组手术与康复相关指标、性激素水平、免疫功能、并发症发生情况。结果观察组手术与康复相关指标均优于对照组,差异均有统计学意义(P均<0.05)。治疗后,观察组促卵泡生成激素为(6.74±1.71)mIU/mL、促黄体生成素为(7.70±1.54)mIU/mL,低于对照组的(9.77±1.89)mIU/mL、(9.10±1.78)mIU/mL,观察组的雌二醇为(61.34±7.29)pmol/L,高于对照组的(43.28±7.14)pmol/L,差异均有统计学意义(t=7.481,3.559,11.111;P均<0.05)。观察组免疫球蛋白G、血清补体C3、白细胞介素-4水平均高于对照组,白细胞介素-2水平低于对照组,差异均有统计学意义(P均<0.05)。两组患者并发症发生率对比,差异无统计学意义(P>0.05)。结论子宫肌瘤患者行腹腔镜下子宫全切术治疗具有创伤小等优势,不会严重损害患者机体的免疫功能,不仅对其术后恢复有积极影响,且不会增加并发症风险,保证预后安全性。Objective The prognosis of patients with uterine fibroids undergoing laparoscopic total hysterectomy was analyzed.Methods The clinical data of 78 patients with uterine fibroids admitted to Jiangdu District Maternal and Child Health Hospital from January 2022 to April 2024 were retrospectively selected.They were divided into different treatment groups,those who received traditional open hysterectomy as the control group(n=37)and those who received laparoscopic total hysterectomy as the observation group(n=41).The operation and rehabilitation related indexes,sex hormone levels,immune function and complications were compared between the two groups.Results The operation and rehabilitation related indexes of the observation group were better than those of the control group,and the differ-ences were statistically significant(all P<0.05).After treatment,the levels of follicle-stimulating hormone and luteiniz-ing hormone in the observation group were(6.74±1.71)mIU/mL and(7.70±1.54)mIU/mL,respectively,which were lower than those in the control group[(9.77±1.89)mIU/mL and(9.10±1.78)mIU/mL],the level of estradiol in the ob-servation group was(61.34±7.29)pmol/L,which was higher than that of the control group(43.28±7.14)pmol/L,and the differences were statistically significant(t=7.481,3.559,11.111;all P<0.05).The levels of immunoglobulin G,se-rum complement C3 and interleukin-4 in the observation group were higher than those in the control group,and the level of interleukin-2 was lower than that in the control group,the differences were statistically significant(all P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).Conclu-sion Laparoscopic total hysterectomy for patients with uterine fibroids has the advantages of less trauma and no seri-ous damage to the immune function of the patient's body.It not only has a positive impact on its postoperative recov-ery,but also does not increase the risk of complications and ensure the safety of prognosis.

关 键 词：子宫肌瘤 腹腔镜下子宫全切术 性激素指标 免疫功能 并发症 

分 类 号：R713.42[医药卫生—妇产科学]