对比开腹胆囊切除术与腹腔镜胆囊切除术在胆囊结石治疗中的临床效果  

Comparison of the Clinical Effects of Open Cholecystectomy and Laparo⁃scopic Cholecystectomy in the Treatment of Gallbladder Stones

作　　者：范巍 胡飞 FAN Wei;HU Fei(Department of General Surgery,Haimen District Hospital of Traditional Chinese Medicine,Nantong,Jiangsu,226100,China)

机构地区：[1]江苏省南通市海门区中医院普外科,江苏南通226100

出　　处：《中外医疗》2025年第2期41-45,共5页China & Foreign Medical Treatment

摘　　要：目的 对比开腹胆囊切除术与腹腔镜胆囊切除术在治疗胆囊结石中的临床效果。方法 随机选取2022年1月—2024年5月江苏省南通市海门区中医院收治的80例胆囊结石患者为研究对象,根据不同手术方式分为开腹组以及腔镜组,每组各40例。开腹组采用开腹胆囊切除术治疗,腔镜组采用腹腔镜胆囊切除术治疗。对比两组手术相关指标、炎症因子水平、胆红素水平、并发症发生情况。结果 腔镜组患者术中失血量低于开腹组,手术操作时间、首次排气时间、首次进食时间、住院时间均短于开腹组,差异均有统计学意义(P均<0.05)。术后,两组患者的炎症因子水平(血清C反应蛋白、降钙素原、白细胞介素-6)均高于术前,但腔镜组炎性因子水平(血清C反应蛋白、降钙素原、白细胞介素-6)均低于开腹组,差异均有统计学意义(P均<0.05)。术后,两组胆红素水平低于术前,腔镜组胆红素水平低于开腹组,并发症总发生率5.00%(2/40)低于开腹组的20.00%(8/40),差异均有统计学意义(P均<0.05)。结论 相较于开腹胆囊切除术,腹腔镜胆囊切除术在治疗胆囊结石时展现出更显著的优势,其手术创伤较小,患者术后恢复迅速,同时能有效改善胆红素水平,并能明显降低术后炎症反应及并发症发生率。Objective To compare the clinical effect of open cholecystectomy and laparoscopic cholecystectomy in the treatment of gallstones.Methods From January 2022 to May 2024,80 patients with gallbladder stones admitted to Haimen District Hospital of Traditional Chinese Medicine,Nantong City,Jiangsu Province were randomly selected as the research objects.According to different surgical methods,the patients were divided into an open laparotomy group and a laparoscopic group,with 40 cases in each group.The open group was treated with open cholecystectomy,and the laparoscopic group was treated with laparoscopic cholecystectomy.The operation-related indicators,inflammatory factor levels,bilirubin levels,and complications were compared between the two groups.Results In the laparoscopic group,the intraoperative blood loss was lower than that in the open laparotomy group,the operation time,the time to first flatus,the time to first oral intake,and the length of hospital stay were all shorter than those in the open laparotomy group,and the differences were statistically significant(all P<0.05).After the operation,the levels of inflamma‐tory factors(serum C-reactive protein,procalcitonin,and interleukin-6)in both groups were higher than those before the operation,and the levels of inflammatory factors(serum C-reactive protein,procalcitonin,and interleukin-6)in the laparoscopic group were all lower than those in the open laparotomy group,and the differences were statistically significant(all P<0.05).After the operation,the bilirubin levels in both groups were lower than those before the operation,the bilirubin level in the laparoscopic group was lower than that in the open laparotomy group,and the total complication rate was 5.00%(2/40)in the laparoscopic group,which was lower than 20.00%(8/40)in the open laparotomy group,and the differences were all statistically significant(all P<0.05).Conclusion Compared with open cholecystectomy,laparoscopic cholecystectomy shows more significant advantages in the treatment of gallstones.The

关 键 词：开腹胆囊切除术 腹腔镜胆囊切除术 胆囊结石 临床效果 并发症 

分 类 号：R6[医药卫生—外科学]