左心室心肌做功指数联合血肌酐水平对慢性肾衰竭患者心功能的评估价值  

The Value of Left Ventricular Work Index Combined with Serum Creatinine in Assessing Cardiac Function in Chronic Renal Failure Patients

作　　者：周倩 张晋玮 ZHOU Qian;ZHANG Jinwei(Department of Cardiology,the First Ward,Nanyang Central Hospital,Nanyang Henan 473000)

机构地区：[1]南阳市中心医院心血管内科一病区,河南南阳473000

出　　处：《医学临床研究》2025年第3期398-400,404,共4页Journal of Clinical Research

摘　　要：【目的】探讨左心室心肌做功指数(Tei指数)联合血肌酐(Scr)对慢性肾衰竭(CRF)患者心功能的评估价值。【方法】141例CRF患者,其中心功能分级Ⅰ~Ⅱ级109例(A组)、Ⅲ~Ⅳ级32例(B组),比较两组患者Tei指数、Scr水平,分析影响CRF患者心功能分级的相关因素。【结果】B组患者的Tei指数、Scr水平均高于A组(P<0.05)。A组左心室射血分数(LVEF)高于B组,尿酸、心肌肌钙蛋白I(cTnI)、N末端B型脑钠肽前体(NT-proBNP)水平均低于B组(P<0.05)。Logistic回归分析结果显示:Tei指数、Scr、LVEF、NT-proBNP水平是CRF患者心功能分级的影响因素(P<0.05)。Tei指数和Scr两者联合评估CRF患者心功能分级的灵敏度、特异度及曲线下面积(AUC)均高于两者单独检测(均P<0.05)。【结论】Tei指数联合Scr评估CRF患者心功能分级效能良好,具有一定的临床价值。【Objective】To investigate the value of the left ventricular work index(Tei index)combined with serum creatinine(Scr)in assessing cardiac function in chronic renal failure(CRF)patients.【Methods】A total of 141 CRF patients were included,with 109 patients in functional classⅠ-Ⅱ(Group A)and 32 patients in functional classⅢ-Ⅳ(Group B).Tei index and Scr level were compared between the two groups,and factors affecting the cardiac function classification of CRF patients were analyzed.【Results】The Tei index and Scr level in Group B were significantly higher than those in Group A(P<0.05).Group A had higher left ventricular ejection fraction(LVEF)level than Group B,while uric acid,cardiac troponin I(cTnI),and N-terminal pro B-type natriuretic peptide(NT-proBNP)levels in Group A were significantly lower compared to Group B(P<0.05).Logistic regression analysis showed that Tei index,Scr,LVEF,and NT-proBNP levels were significant factors influencing the cardiac function classification of CRF patients(P<0.05).The combined assessment of Tei index and Scr showed even higher sensitivity,specificity,and area under the curve(AUC)for evaluating the cardiac function classification of CRF patients compared to each test alone(P<0.05).【Conclusion】The combined assessment of Tei index and Scr is effective in evaluating the cardiac function classification of CRF patients and holds significant clinical value.

关 键 词：肾功能衰竭 慢性 心肌 肌酸酐 心脏功能试验 

分 类 号：R692.5[医药卫生—泌尿科学]