抑亢汤联合耳穴压籽治疗多囊卵巢综合征临床研究  

Clinical Study on Yikang Decoction Combined with Auricular Point Seed-Pressing for Polycystic Ovary Syndrome

作　　者：陈贤微 徐秀丽 胡欣欣[1] CHEN Xianwei;XU Xiuli;HU Xinxin(Wenzhou TCM Hospital of Zhejiang Chinese Medical University,Wenzhou Zhejiang 325000,China)

机构地区：[1]浙江中医药大学附属温州市中医院,浙江温州325000

出　　处：《新中医》2025年第7期130-134,共5页New Chinese Medicine

基　　金：浙江中医药大学科研专属项目(2022FSYYZZ28)。

摘　　要：目的:观察抑亢汤联合耳穴压籽治疗多囊卵巢综合征(PCOS)的疗效。方法:选取2023年1月—2024年1月温州市中医院收治的96例PCOS患者,按随机数字表法分为耳穴组、中药组、联合组各32例。3组均给予常规治疗措施,耳穴组采用耳穴压籽治疗,中药组采用抑亢汤治疗,联合组采用抑亢汤联合耳穴压籽治疗。3组均连续治疗3个月。比较3组临床疗效及不良反应发生情况,比较3组治疗前后中医证候积分、卵巢储备功能、性激素[卵泡生成激素(FSH)、黄体生成激素(LH)、雌二醇(E2)]水平的变化。结果:联合组临床疗效总有效率为93.75%(30/32),耳穴组临床疗效总有效率为65.63%(21/32),中药组临床疗效总有效率为71.88%(23/32),联合组临床疗效总有效率高于耳穴组及中药组,差异有统计学意义(P<0.05)。治疗后,3组中医证候积分均较治疗前下降(P<0.05),联合组中医证候积分均低于耳穴组及中药组(P<0.05)。治疗后,3组卵巢体积及卵泡数均较治疗前减小(P<0.05),联合组卵巢体积及卵泡数均小于耳穴组及中药组(P<0.05)。治疗后,3组FSH水平均较治疗前升高(P<0.05),LH、E2水平均较治疗前下降(P<0.05);联合组FSH水平高于耳穴组、中药组(P<0.05),LH、E2水平均低于耳穴组、中药组(P<0.05)。3组治疗期间均未出现明显不良反应。结论:抑亢汤联合耳穴压籽治疗PCOS的疗效确切,可改善卵巢储备功能,调节性激素水平,安全性高。Objective:To observe the curative effect of the combination use of Yikang Decoction and auricular point seed-pressing on polycystic ovary syndrome(PCOS).Methods:A total of 96 PCOS patients admitted to Wenzhou Hospital of Traditional Chinese Medicine from January 2023 to January 2024 were selected and divided into the auricular point group,the Chinese medicinal group and the combination group according to the random number table method,with 32 cases in each group.The three groups were given conventional treatment,the auricular point group was additionally treated with auricular point seed-pressing,the Chinese medicinal group was additionally treated with Yikang Decoction,and the combination group was additionally treated with Yikang Decoction combined with auricular point seed-pressing.The three groups were treated for three months.The clinical effects and the incidence of adverse reactions,and the changes in traditional Chinese medicine syndrome scores,ovarian reserve and levels of sex hormones[follicle-stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)]before and after treatment were compared among the three groups.Results:The total clinical effective rate was 93.75%(30/32)in the combination group,higher than that of 65.63%(21/32)in the auricular point group and 71.88%(23/32)in the Chinese medicinal group,the difference was statistically significant(P<0.05).After treatment,the traditional Chinese medicine syndrome scores in the three groups were reduced when compared with those before treatment(P<0.05),and the above scores in the combination group were lower than those in the auricular point group and the Chinese medicinal group(P<0.05).After treatment,the ovarian volume and the number of follicles in the three groups were dwindled when compared with those before treatment(P<0.05),and the ovarian volume and the number of follicles in the combination group were lower than those in the auricular point group and the Chinese medicinal group(P<0.05).After treatment,the FSH levels in the three groups we

关 键 词：多囊卵巢综合征 肝经湿热型 抑亢汤 耳穴压籽 卵巢储备功能 

分 类 号：R271[医药卫生—中医妇科学] R711.75[医药卫生—中医学]