血必净联合抗菌药物治疗重症肺部感染的临床价值  

Clinical Value of Xuebijing Combined with Antibiotics in the Treatment of Severe Pulmonary Infection

作　　者：沈立飞 SHEN Lifei(Department of Respiratory,Liyang Hospital of Chinese Medicine,Liyang 213300,Jiangsu,China)

机构地区：[1]溧阳市中医医院呼吸科,江苏溧阳213300

出　　处：《世界复合医学(中英文)》2024年第12期49-52,共4页World Journal of Complex Medicine

摘　　要：目的探讨重症肺部感染应用血必净联合抗菌药物治疗的价值。方法根据不同的治疗方法,将2022年5月—2023年12月溧阳市中医医院收治的70例重症肺部感染患者分为两组。研究组(35例)采用血必净联合抗菌药物治疗,对照组(35例)采用常规抗感染治疗,比较两组治疗总有效率、降钙素原(procalcitonin,PCT)、超敏C反应蛋白(hypersensitive C-reactive protein,hs-CRP)、不良反应发生率、病情恢复时间。结果研究组治疗总有效率为97.14%(34/35),相比对照组的71.43%(25/35)更高,差异有统计学意义(χ^(2)=8.736,P<0.05)。治疗后,相比于对照组,研究组PCT、hs-CRP水平及不良反应发生率均更低,咳嗽消失时间、发热消失时间、肺部啰音消失时间、痰菌转阴时间均更短,差异均有统计学意义(P均<0.05)。结论血必净联合抗菌药物应用在重症肺部感染患者中可减轻患者机体炎性反应,提高治疗有效率和安全性。Objective To explore the value of Xuebijing combined with antibiotics in the treatment of se-vere pulmonary infection.Methods According to different treatment methods,a total of 70 patients with severe pulmonary infection admitted to Liyang Hospital of Chinese Medicine from May 2022 to December 2023 were selected and divided into two groups.The study group(35 cases)was treated with Xuebijing combined with anti-biotics,and the control group(35 cases)was treated with conventional anti-infective therapy.The total effective rate of treatment,procalcitonin(PCT),hypersensitive C-reactive protein(hs-CRP)levels,incidence of adverse reactions and recovery time of the two groups were compared.Results The total effective rate of treatment in the study group was 97.14%(34/35),compared with 71.43%(25/35)in the control group were higher,and the differ-ence was statistically significant(χ^(2)=8.736,P<0.05).After treatment,compared with the control group,the lev-els of PCT,hs-CRP and the incidence of adverse reactions in the study group were lower,the cough disappear-ance time,fever disappearance time,lung rale disappearance time and sputum negative conversion time were shorter,and the differences were statistically significant(all P<0.05).Conclusion The application in patients with severe lung infection can reduce the inflammatory reaction and improve the safety of treatment.

关 键 词：血必净 重症肺部感染 抗菌药物 治疗 

分 类 号：R563.1[医药卫生—呼吸系统]