机构地区:[1]河南中医药大学第一附属医院妇产科,郑州450000
出 处:《临床医学》2025年第2期23-26,共4页Clinical Medicine
摘 要:目的 分析妊娠期糖尿病(GDM)患者孕前体质指数(BMI)、孕期体质量增加(GWG)量与不良妊娠结局、并发症的关系。方法 选择2020年1月至2023年12月河南中医药大学第一附属医院收治的60例GDM患者为研究对象。将孕前BMI正常的42例孕妇作为正常组,将孕前BMI偏重及肥胖的18例孕妇作为偏重及肥胖组;同时将GWG正常的43例孕妇记为增重正常组,将GWG过度的17例孕妇记为增重过度组。分析孕前不同BMI、GWG的GDM患者的不良妊娠结局发生率及并发症发生率,研究孕前不同BMI、GWG与不良妊娠结局发生率及并发症发生率的关系。结果 偏重及肥胖组不良妊娠结局中胎儿窘迫发生率[16.67%(3/18)]、巨大儿发生率[22.22%(4/18)]、并发症妊娠期高血压发生率[27.78%(5/18)]高于正常组[0.00%(0/42)、2.38%(1/42)、0.00%(0/42)],差异有统计学意义(P<0.05)。增重过度组不良妊娠结局中胎儿窘迫发生率[17.65%(3/17)]、巨大儿发生率[29.41%(5/17)]、并发症妊娠期高血压发生率[23.53%(4/17)]高于增重正常组[0.00%(0/43)、0.00%(0/43)、2.33%(1/43)],差异有统计学意义(P<0.05)。Pearson分析结果显示,孕前不同BMI(r=0.492,r=0.461)、GWG(r=0.624,r=0.346)与并发症发生率及不良妊娠结局发生率呈正相关(P<0.05)。结论 孕前BMI偏高、GWG过度的GDM患者不良妊娠结局及并发症发生率较高,提示临床需通过合理的体质量管理和血糖控制以减少不良妊娠结局和并发症的发生。Objective To analyze the relationship between pre-pregnancy body mass index(BMI),amount of weight gained during pregnancy(GWG)and adverse pregnancy outcomes and complications in patients with gestational diabetes mellitus(GDM).Methods Sixty patients with GDM in the First Affiliated Hospital of Henan University of Chinese Medicine from January 2020 to December 2023 were selected as the study objects.Forty-two pregnant women with normal BMI before pregnancy were selected as normal group,and 18 pregnant women with overweight and obese BMI before pregnancy were selected as overweight and obese group.At the same time,43 pregnant women with normal CWG increase were classified as normal weight gain group,and 17 pregnant women with excessive GWG increase were classified as excessive weight gain group.The incidences of adyerse pregnancy outcomes and complications in GDM patients with different preconception BMI and GWG were analyzed,and to study the relationship between different preconception BMI and GWG and the incidences of adverse pregnancy outcomes and complications were studied.Results The incidence of fetal distress[16.67%(3/18)],macrosomia[22.22%(4/18)]and complication pregnancy hypertension[27.78%(5/18)]in the overweight and obese groups were higher than those in the normal group[0.00%(0/42),2.38%(1/42)and 0.00%(0/42)],the differences were significant(P<0.05).The incidence of fetal distress[17.65%(3/17)],macrosomia[29.41%(5/17)]and complication pregnancy hypertension[23.53%(4/17)] in the excessive weight gain group was higher than that in the normal weight gain group[0.00%(0/43),0.00%(0/43),2.33%(1/43)],the differences were significant(P<0.05).Pearson analysis showed that different preconception BMI(r=0.492,r=0.461)and GWG(r=0.624,r=0.346)were positively correlated with the incidence of complications and adverse pregnancy outcomes(P<0.05).ConclusionssGDM patients with high pre-pregnancy BMI and excessive increase in GWG have higher rates of adverse pregnancy outcomes and complications,suggesting that reasonable w
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