CT灌注成像评估老年冠心病患者PCI成功的价值  

Assessment Value of CT Perfusion Imaging in Evaluating the Success of PCI in Elderly Patients with Coronary Heart Disease

作　　者：刘月 卢万玲 马秋月 杨岚 LIU Yue;LU Wanling;MA Qiuyue;YANG Lan(Interventional Operating Room,the 7th People’s Hospital of Zhengzhou,Zhengzhou 450000,China;Imaging Department,the 7th People’s Hospital of Zhengzhou,Zhengzhou 450000,China)

机构地区：[1]郑州市第七人民医院介入手术室,河南郑州450000 [2]郑州市第七人民医院影像科,河南郑州450000

出　　处：《河南医学研究》2025年第6期1013-1017,共5页Henan Medical Research

摘　　要：目的探讨CT灌注成像评估老年冠心病患者经皮冠状动脉介入治疗(PCI)成功的价值。方法选取2021年6月至2023年6月在郑州市第七人民医院接受PCI治疗的100例老年冠心病患者,分为成功组和失败组,比较两组患者的一般资料、CT血管成像定量参数、CT灌注成像定量参数、血清胱抑素C和半乳糖凝集素水平。采用Pearson相关分析和logistic回归分析探讨CT灌注成像定量参数与PCI成功相关性。结果成功组和失败组在年龄、性别、吸烟史、高血压史、糖尿病史、血清胱抑素C和半乳糖凝集素水平方面差异无统计学意义(P>0.05)。成功组的CT血管成像定量参数(最小管腔面积、最小管腔直径、管腔直径狭窄百分比)与失败组差异有统计学意义(P<0.05)。成功组的CT灌注成像定量参数(心肌灌注缺损面积、心肌灌注缺损程度)与失败组差异有统计学意义(P<0.05)。Pearson相关分析显示,CT灌注成像定量参数与PCI成功呈负相关(r=-0.67,P<0.01)。logistic回归分析显示,CT灌注成像定量参数是PCI成功的独立预测因子(OR=0.82,95%CI=0.74~0.91,P<0.01)。结论CT灌注成像能够全面评价老年冠心病患者的冠状动脉心肌灌注情况,对预测PCI治疗成败具有重要价值。Objective To explore the application value of CT perfusion imaging in evaluating the success of percutaneous coronary intervention(PCI)in elderly patients with coronary heart disease.Methods A total of 100 elderly patients with coronary heart disease who underwent PCI treatment in the 7th People’s Hospital of Zhengzhou from June 2021 to June 2023 were selected and divided into success group and failure group.The general data,CT angiography quantitative parameters,CT perfusion imaging quantitative parameters,serum cystatin C and galectin levels of the two groups were compared.Pearson correlation analysis and logistic regression analysis were used to explore the correlation between CT perfusion imaging quantitative parameters and PCI success.Results There was no statistical difference in age,gender,smoking history,hypertension history,diabetes history,serum cystatin C and galectin levels between the success group and the failure group(P>0.05).The CT angiography quantitative parameters(minimum lumen area,minimum lumen diameter,lumen diameter stenosis percentage)of the success group were significantly different from those of the failure group(P<0.05).The CT perfusion imaging quantitative parameters(myocardial perfusion defect area,myocardial perfusion defect degree)of the success group were significantly different from those of the failure group(P<0.05).Pearson correlation analysis showed that CT perfusion imaging quantitative parameters were negatively correlated with PCI success(r=-0.67,P<0.01).Logistic regression analysis showed that CT perfusion imaging quantitative parameters were independent predictors of PCI success(OR=0.82,95%CI=0.74-0.91,P<0.01).Conclusion CT perfusion imaging can comprehensively evaluate myocardial perfusion status of elderly patients with coronary heart disease,and has important value in predicting the success or failure of PCI treatment.

关 键 词：冠心病 老年人 CT灌注成像 经皮冠状动脉介入治疗 心肌灌注 预测 

分 类 号：R816.2[医药卫生—放射医学]