2017—2023年云南省棘球蚴病综合防治措施实施效果分析  

Effectiveness of comprehensive echinococcosis control measures in Yunnan Province from 2017 to 2023

作　　者：李奔福[1] 吴方伟[1] 字金荣 严信留 彭佳[1] 王正青 李建雄[1] 徐倩 李永飞 杨亚明[1] LI Benfu;WU Fangwei;ZI Jinrong;YAN Xinliu;PENG Jia;WANG Zhengqing;LI Jianxiong;XU Qian;LI Yongfei;YANG Yaming(Yunnan Institute of Parasitic Diseases,Yunnan Provincial Center of Malaria Research,Yunnan Provincial Collaborative Innovation Center for Public Health and Disease Prevention and Control,Yunnan Provincial Key Laboratory of Vector-borne Diseases Control and Research,Pu’er 665000,Yunnan,China)

机构地区：[1]云南省寄生虫病防治所,云南省疟疾研究中心,云南公共卫生与疾病防控协同创新中心,大理学大学病原与媒介生物研究所(普洱分部),云南普洱665000

出　　处：《中国寄生虫学与寄生虫病杂志》2025年第1期20-25,共6页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：国家卫生健康委员会棘球蚴病防治研究重点实验室开放课题(2021WZK1001)。

摘　　要：目的分析2017—2023年云南省棘球蚴病综合防治措施实施效果,为云南省制定棘球蚴病防控措施提供参考依据。方法2017年在云南省9个州(市)24个县(市、区)实施中央重大疾病棘球蚴病防控项目,在流行区建立棘球蚴病监测和实验室检测体系、实行病例规范管理、进行病例个案流行病学调查、对疫点进行调查处置、防控传染源犬、防控中间宿主动物、健康科普。收集2016—2023年云南省棘球蚴病综合防治措施、防治和监测报表数据,以人群棘球蚴病患病率、犬棘球绦虫粪抗原阳性率、家畜棘球蚴病患病率、人群棘球蚴病防治知识知晓率为评价指标,采用SPSS 21.0统计学软件进行分析,应用χ^(2)检验进行趋势性分析,以2016年度调查数据为基线,计算各年度的相对风险度,评价云南省棘球蚴病综合防治措施实施效果。结果2017—2023年云南省建立了1个棘球蚴病防控工作站、2个省级棘球蚴病检测参比实验室,人群棘球蚴病B超筛查183万人次、病例随访365次和病例个案流行病学调查254次、病例规范管理率为100%、疫点调查处置5个。2023年人群棘球蚴病患病率(1.42/10万,11/774609)与基线(38.17/10万,24/62874)相比下降了96.28%,人群患病率差异有统计学意义(χ^(2)=187.881,P<0.05)。居民棘球蚴病防治知识知晓率从基线的43.50%(5075/11668)提高至2023年89.20%(6680/7489)(χ^(2)=922.835,P<0.05),小学生棘球蚴病防治知识知晓率从2019年77.86%(2687/3451)提高至2023年95.21%(7097/7454)(χ^(2)=44.170,P<0.05)。犬棘球绦虫粪抗原阳性率从2017的4.38%(186/4246)下降至2023年1.68%(141/8392)(χ^(2)=367.928,P<0.05),家畜动物患病率从基线的0.23%(8/3472)下降至2023年0.12%(7/5663)(χ^(2)=1.492,P>0.05)。相对危险度分析显示,2023年较2017年人群棘球蚴病患病风险下降了97.99%,2023年传染源犬传播风险度与2018年相比下降了90.76%。各年度家畜动物棘球蚴病患病风险比差Objective To evaluate the effectiveness of comprehensive echinococcosis control measures in Yun-nan Province from 2017 to 2023,so as to provide insights into formulation of the echinococcosis control strategy in the province in the future.Methods The central government fiscal transfer payment program for echinococcosis pre-vention and control was implemented across 24 counties(cities,districts)in 9 prefectures(cities)of Yunnan Province in 2017,and establishment of the echinococcosis surveillance and laboratory testing system,standardized management of echinococcosis patients,case investigation,investigation and disposal of foci,management of dogs and intermediate host animals and health education were performed in echinococcosis-endemic areas.The comprehensive echinococcosis control measures,echinococcosis control reports and echinococcosis surveillance reports were collected in Yunnan Province from 2016 to 2023,and the prevalence of human echinococcosis,positive rate of Echinococcus coproantigen in dogs,prevalence of echinococcosis in livestock,and awareness of echinococcosis control knowledge among residents were estimated.All analyses were performed with the statistical software SPSS 21.0,and the trends were tested with chi-square test.In addition,the relative risk was calculated from 2017 to 2023 based on the 2016 data,in order to evaluate the effectiveness of comprehensive echinococcosis control measures in Yunnan Province.Results An echino-coccosis control workstation and 2 province-level echinococcosis testing reference laboratories were built in Yunnan Province during the period between 2017 and 2023,when B-mode ultrasonography screening for human echinococcosis among 1.83 million person-times,365 times of follow-up of echinococcosis patients,254 case investigations,a 100%pro-portion of standardized case management and investigation and disposal of 5 foci were conducted.The prevalence of human echinococcosis reduced from 38.17/105(24/62874)at baseline to 1.42/105(11/774609)in 2023,with a reduction of 96.2

关 键 词：棘球蚴病 综合防治 措施 效果 云南省 

分 类 号：R523.32[医药卫生—内科学]