儿童高血压药物治疗研究进展  

Advances in the drug therapy for pediatric hypertension

作　　者：胡波 石琳[2] Hu Bo;Shi Lin(Capital Institute of Pediatrics,Peking University,Beijing 100020,China;Department of Cardiology,Children's Hospital,Capital Institute of Pediatrics,Beijing 100020,China)

机构地区：[1]北京大学首都儿科研究所教学医院,100020 [2]首都儿科研究所附属儿童医院心血管内科,北京100020

出　　处：《国际儿科学杂志》2025年第2期73-77,共5页International Journal of Pediatrics

基　　金：北京市科学技术委员会首都临床诊疗技术研究及转化应用项目(Z211100002921035);北京市卫生健康委员会首都卫生发展科研专项(首发2022-3-2105)。

摘　　要：随着社会的发展与对疾病认知水平的提高,高血压已成为全球范围内的重大公共卫生问题。儿童原发性高血压近年来发病率逐年升高,其起病隐匿、进展缓慢,早期症状不明显,导致就诊率低,易发展为成年期高血压,与成人期心血管事件相关。药物治疗是儿童原发性高血压治疗的重要方法之一,但是大部分成人使用的降血压药物应用在儿科缺乏有效性与安全性验证。近年来,随着儿童高血压研究的深入,其药物治疗也取得了一定进展,该文从目前国内外儿童高血压药物临床分类、诊断标准、药物治疗适应证及个体化治疗等方面对儿童高血压的药物治疗进展进行综述。With the development of society and the improvement of disease cognition level,hypertension has become a major public health issue worldwide.In recent years,the incidence of pediatric primary hypertension has increased year by year.The onset is obscure,and progress is slow,and early symptoms are difficult to detect,leading to low outpatient rate.In the end,it will develop to adult hypertension,which is related to cardiovascular diseases.Drug therapy is one of the important methods for primary pediatric hypertension,but most of medications used to cure adult hypertension lack pediatric verification of efficacy and safety.But in recent years,with the progress of research on pediatric hypertension,the medication therapy has also made impressive progress.This article reviews the progress of medication treatment for pediatric hypertension from aspects of diagnostic criteria,clinical classification,indication for medical therapy,and individualized therapy of medications for pediatric hypertension in China and abroad.

关 键 词：儿童 高血压 药物 治疗 

分 类 号：R725.4[医药卫生—儿科]