2021—2023年北京市发热伴血小板减少综合征本地感染病例的流行病学特征  

Epidemiological characteristics of local cases of severe fever with thrombocytopenia syndrome in Beijing,2021-2023

作　　者：孙玉兰[1] 窦相峰[1] 任振勇[1] 李丹 金昊源 李爽[1] 陈艳伟[1] 张代涛[1] SUN Yulan;DOU Xiangfeng;REN Zhenyong;LI Dan;JIN Haoyuan;LI Shuang;CHEN Yanwei;ZHANG Daitao(Beijing Center for Disease Prevention and Control,Beijing 100013,China)

机构地区：[1]北京市疾病预防控制中心,100013

出　　处：《首都公共卫生》2025年第1期56-60,共5页Capital Journal of Public Health

摘　　要：目的了解北京市2021—2023年发热伴血小板减少综合征(severe fever with thrombocytopenia syndrome,SFTS)的流行病学特征,为北京市防控该疾病提供依据。方法收集分析SFTS病例的个案资料,对阳性样本进行全基因测序,并进行遗传进化分析。结果2021—2023年,北京市共报告9例本地感染病例,发病时间均在5—10月。男性6例,女性3例,年龄分布在40~<70岁,职业以农民为主。病例分布在5个区,平谷区发病数最多,有5例,存在一定的地域聚集性,平谷区还发生1起动物传人的聚集性疫情。测序及遗传进化分析结果显示,北京市的病例分属于A基因型和B基因型,未发现重配毒株。结论北京市SFTS病例为散发病例,有一定的地域聚集性,流行毒株为A基因型和B基因型。Objective To understand the epidemiological characteristics of severe fever with thrombocytopenia syndrome(SFTS)in Beijing from 2021 to 2023,providing insights for disease prevention and control in the city.Methods SFTS case data were collected and analyzed.Whole-genome sequencing was conducted on positive samples,and genetic evolution analysis was performed.Results A total of 9 locally infected cases were reported in Beijing from 2021 to 2023,with disease onset between May and October.The cases included 6 males and 3 females,aged 40-<70,predominantly farmers.The cases were distributed across five districts,with Pinggu district having the highest number of cases(5 cases),indicating a certain degree of geographical clustering.There was also a cluster of animal-to-human transmission in Pinggu district.Sequencing and genetic evolution analysis revealed that the cases in Beijing belonged to genotype A or genotype B,with no reassorting strains detected.Conclusions The cases in Beijing are highly sporadic,with a certain degree of geographical clustering,and the epidemic strains are genotype A and genotype B.

关 键 词：发热伴血小板减少综合征 本地感染 聚集性疫情 基因型 

分 类 号：R512.8[医药卫生—内科学]