Unlocking the secrets of exercise:A pathway to enhanced insulin sensitivity and skeletal muscle health in type 2 diabetes  

作　　者：Juleen R.Zierath Aidan J.Brady Kirstin A.Macgregor Joaquin Ortiz de Zevallos Ben Stocks 

机构地区：[1]Section of Integrative Physiology,Department of Molecular Medicine and Surgery,Karolinska Institutet,Stockholm 17165,Sweden [2]Section of Integrative Physiology,Department of Physiology and Pharmacology,Karolinska Institutet,Stockholm 17165,Sweden [3]Novo Nordisk Foundation Center for Basic Metabolic Research,University of Copenhagen,Copenhagen 2200,Denmark

出　　处：《Journal of Sport and Health Science》2025年第2期71-74,共4页运动与健康科学(英文)

基　　金：supported by the Swedish Research Council(201500165);a Wallenberg Scholars Award from the Knut and Alice Wallenberg Foundation(KAW 2023.0312);The Novo Nordisk Foundation Center for Basic Metabolic Research is an independent research center at the University of Copenhagen,partially funded by an unrestricted donation from the Novo Nordisk Foundation(NNF23SA0084103).

摘　　要：1.Exercise enhances muscle function and insulin sensitivity Skeletal muscle plays a fundamental role in not only locomotion,but also systemic metabolism.In people with type 2 diabetes,skeletal muscle is a major site of insulin resistance,with impaired insulin signaling and reduced glucose transport activity contributing to metabolic dysfunction.

关 键 词：impaired insulin signaling metabolic dysfunction muscle function type diabetes insulin sensitivity reduced glucose transport activity skeletal muscle 

分 类 号：R587.1[医药卫生—内分泌]