Interplay between physical activity volume and intensity with modeled life expectancy in women and men:A prospective cohort analysis  

作　　者：Francesco Zaccardi Alex V.Rowlands Paddy C.Dempsey Cameron Razieh Joe Henson Jonathan Goldney Benjamin D.Maylor Atanu Bhattacharjee Yogini Chudasama Charlotte Edwardson Jari A.Laukkanen Ulf Ekelund Melanie J.Davies Kamlesh Khunti Thomas Yates 

机构地区：[1]Diabetes Research Centre,University of Leicester,Leicester LE54PW,UK [2]Leicester Real World Evidence Unit,Diabetes Research Centre,University of Leicester,Leicester LE54PW,UK [3]NIHR Leicester Biomedical Research Centre,University Hospitals of Leicester NHS Trust,Leicester LE15WW,UK [4]Institute for Physical Activity and Nutrition(IPAN),School of Exercise and Nutrition Sciences,Deakin University,Geelong VIC 3220,Australia [5]Department of Medicine,Central Finland Health Care Hospital District 40620 Jyväskylä,Finland [6]Institute of Clinical Medicine,Department of Medicine,University of Eastern Finland 70210 Kuopio,Finland [7]Institute of Public Health and Clinical Nutrition,University of Eastern Finland 70210 Kuopio,Finland [8]Department of Sports Medicine,Norwegian School of Sports Sciences 0863 Oslo,Norway [9]Department of Chronic Diseases and Ageing,Norwegian Institute of Public Health 0473 Oslo,Norway [10]NIHR Applied Research Collaborations East Midlands,University Hospitals of Leicester NHS Trust,Leicester LE15WW,UK

出　　处：《Journal of Sport and Health Science》2025年第1期6-15,共10页运动与健康科学(英文)

基　　金：funded by the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre (BRC);the Applied Research Collaborations East Midlands (ARC-EM);supported by a UKRI project grant (MR/T031816/1)。

摘　　要：Background There is a lack of research examining the interplay between objectively measured physical activity volume and intensity with life expectancy.The purpose of the study was to investigate the interplay between objectively measured PA volume and intensity profiles with modeled life expectancy in women and men within the UK Biobank cohort study and interpret findings in relation to brisk walking.Methods Individuals from UK Biobank with wrist-worn accelerometer data were included.The average acceleration and intensity gradient were extracted to describe the physical activity volume and intensity profile.Mortality data were obtained from national registries.Adjusted life expectancies were estimated using parametric flexible survival models.Results 40,953(57.1%)women(median age=61.9 years)and 30,820(42.9%)men(63.1 years)were included.Over a median follow-up of 6.9 years,there were 1719(2.4%)deaths(733 in women;986 in men).At 60 years,life expectancy was progressively longer for higher physical activity volume and intensity profiles,reaching 95.6 years in women and 94.5 years in men at the 90th centile for both volume and intensity,corresponding to 3.4 additional years(95%confidence interval(95%CI):2.4-4.4)in women and 4.6 additional years(95%CI:3.6-5.6)in men compared to those at the 10th centiles.An additional 10-min or 30-min daily brisk walk was associated with 0.9(95%CI:0.5-1.3)and 1.4 years(95%CI:0.9-1.9)longer life expectancy,respectively,in inactive women;and 1.4 years(95%CI:1.0-1.8)and 2.5(95%CI:1.9-3.1)in inactive men.Conclusion Higher physical activity volumes were associated with longer life expectancy,with a higher physical activity intensity profile further adding to a longer life.Adding as little as a 10-min brisk walk to daily activity patterns may result in a meaningful benefit to life expectancy.

关 键 词：Life expectancy Physical activity intensity Physical activity volume Survival Walking 

分 类 号：R161.7[医药卫生—公共卫生与预防医学]