Enhancing clinical and public health interpretation of accelerometer-assessed physical activity with age-referenced values based on UK Biobank data  

作　　者：Alex V.Rowlands Andrew P.Kingsnorth Bjørge H.Hansen Stuart J.Fairclough Lynne M.Boddy Benjamin D.Maylor Henrik R.Eckmann Borja del Pozo Cruz Nathan P.Dawkins Cameron Razieh Kamlesh Khunti Francesco Zaccardi Tom Yates 

机构地区：[1]Assessment of Movement Behaviours(AMBer)Group,Diabetes Research Centre,Leicester General Hospital,University of Leicester,Leicester LE54PW,UK [2]Diabetes Research Centre,Leicester General Hospital,University of Leicester,Leicester LE54PW,UK [3]National Institute for Health Research(NIHR)Leicester Biomedical Research Centre(BRC),University Hospitals of Leicester National Health Service(NHS)Trust and the University of Leicester,Leicester LE54PW,UK [4]Alliance for Research in Exercise,Nutrition and Activity(ARENA),UniSA Allied Health and Human Performance,University of South Australia,Adelaide SA5001,Australia [5]School of Sport,Health and Exercise Sciences,Loughborough University,Loughborough LE113TU,UK [6]Department of Sport Science and Physical Education,University of Agder,Kristiansand 4604,Norway [7]Movement Behaviours,Health,and Wellbeing Research Group,Department of Sport and Physical Activity,Edge Hill University,Ormskirk L394QP,UK [8]Physical Activity Exchange,Research Institute for Sport and Exercise Sciences,Liverpool John Moores University,Liverpool L35AH,UK [9]Nuffield Department of Population Health&Big Data Institute,University of Oxford,Oxford OX37LF,UK [10]Faculty of Education,University of Cádiz,Cádiz 11519,Spain [11]Biomedical Research and Innovation Institute of Cádiz(IMiBICA)Research Unit,Puerta del Mar University Hospital,University of Cádiz,Cadiz 11009,Spain [12]Centre for Active and Healthy Ageing,Department of Sports Science and Clinical Biomechanics,University of Southern Denmark,Odense 5230,Denmark [13]Bradford Institute for Health Research,Bradford Teaching Hospitals NHS Foundation Trust,Bradford Royal Infirmary,Bradford BD96RJ,UK [14]NIHR Bristol Biomedical Research Centre,University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol,Bristol BS82BN,UK [15]Leicester Real World Evidence Unit,Diabetes Research Centre,Leicester General Hospital,University of Leicester,Leicester LE54PW,UK [16]Office for National Statistics,Newport NP108XG,UK

出　　处：《Journal of Sport and Health Science》2025年第1期27-37,共11页运动与健康科学(英文)

基　　金：supported by the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre and NIHR Applied Research Collaboration East Midlands (ARC EM, (IS-BRC-1215-20010));funded by the National Institute for Health and Care Research Bristol Biomedical Research Centre (IS-BRC-1215-20011);supported by a UKRI research grant (EP/X042464/1)。

摘　　要：Background Higher accelerometer-assessed volume and intensity of physical activity(PA)have been associated with a longer life expectancy but can be difficult to translate into recommended doses of PA.We aimed to:(a)improve interpretability by producing UK Biobank age-referenced centiles for PA volume and intensity;(b)inform public-health messaging by examining how adding recommended quantities of moderate and vigorous PA affect PA volume and intensity.Methods 92,480 UK Biobank participants aged 43-80 years with wrist-worn accelerometer data were included.Average acceleration and intensity gradient were derived as proxies for PA volume and intensity.We generated sex-specific centile curves using Generalized Additive Models for Location Scale and Shape(GAMLSS)and modeled the effect of adding moderate(walking)or vigorous(running)activity on the combined change in the volume and intensity centiles(change in PA profile).Results In men,volume was lower as age increased while intensity was lower after age 55;in women,both volume and intensity were lower as age increased.Adding 150 min of moderate PA weekly(5×30 min walking)increased the PA profile by 4 percentage points.Defining moderate PA as brisk walking approximately doubled the increase(9 percentage points)while 75 min of vigorous PA weekly(5×15 min running)trebled the increase(13 percentage points).Conclusion These UK Biobank reference centiles provide a benchmark for interpretation of accelerometer data.Application of our translational methods demonstrate that meeting PA guidelines through shorter duration vigorous activity is more beneficial to the PA profile(volume and intensity)than longer duration moderate activity.

关 键 词：Physical activity recommendations Average acceleration Intensity gradient MODERATE Vigorous 

分 类 号：R161.7[医药卫生—公共卫生与预防医学]