Polyoxometalate-based peroxidase-like nanozymes  

作　　者：Xiangwei Liu Tiedong Sun Yuan Sun Alina Manshina Lei Wang 

机构地区：[1]College of Chemistry,Chemical Engineering and Resource Utilization,Northeast Forestry University,Harbin,150040,China [2]School of Chemistry and Chemical Engineering,Harbin Institute of Technology,Harbin,150001,China [3]Center of Pharmaceutical Engineering and Technology,Harbin University of Commerce,Harbin,150076,China [4]Institute of Chemistry,Saint Petersburg State University,Universitetskii pr.26,St.Petersburg,Russian Federation

出　　处：《Nano Materials Science》2025年第1期24-48,共25页纳米材料科学(英文版)

基　　金：the National Natural Science Foundation of China(No.52372264,32271609,52073071,51703043);the Natural Science Foundation of Heilongjiang Province of China(No.LH2023B002).

摘　　要：Nanozymes,as a new generation of artificial enzymes,exhibit similar chemical properties,catalytic efficiency,and reaction kinetics to natural enzymes.Nanozymes can offer several advantages over natural enzymes,including the decreased cost,the increased stability,and the enhanced catalytic activity.These advantages have positioned nanozymes as a research focus in the fields of chemistry,materials and biomedicine.Polyoxometalates(POMs)and their composites have been found to possess excellent catalytic capabilities as peroxidase mimics.Given this,this review aims to provide a comprehensive overview of the POM-based nanozymes,covering their structural categorization,evolution,and various applications over the past decade.The dynamic nature of this field would promise the intriguing challenges and opportunities in the future.Additionally,we address the existing issues with the POM-based peroxidase-like enzymes and suggest the potential directions for future research.This review would serve as a valuable resource for researchers seeking to develop the improved therapeutic and diagnostic technologies using the POM-based nanozymes,thereby advancing the fields of biochemistry and materials science.

关 键 词：Polyoxometalates Peroxidase Nanozymes NANOMATERIALS H_(2)O_(2) 

分 类 号：O64[理学—物理化学]