叶酸与新生儿健康及母乳中叶酸研究进展  

Research Progress on Folic Acid Health Effects in Newborns and Folic Acid in Human Milk

作　　者：贾宏信[1] 苏米亚[1] 陈文亮[1] JIA Hongxin;SU Miya;CHEN Wenliang(Dairy Research Institute,Bright Dairy and Food Co.Ltd.,State Key Laboratory of Dairy Biotechnology,Shanghai Engineering Research Center of Dairy Biotechnology,Shanghai 200436,China)

机构地区：[1]乳业生物技术国家重点实验室,上海乳业生物工程技术研究中心,光明乳业股份有限公司乳业研究院,上海200436

出　　处：《乳业科学与技术》2025年第2期35-39,共5页JOURNAL OF DAIRY SCIENCE AND TECHNOLOGY

基　　金：上海市国资委企业创新发展和能级提升项目(2022013)。

摘　　要：叶酸是母乳中一种非常重要的水溶性维生素,是胚胎发育、生长的必需物质。母乳中叶酸常以多谷氨酸盐(≥4个谷酰基残基)形式存在,如5-亚甲基四氢叶酸。叶酸缺乏可能导致出生缺陷,如神经管畸形、先天性心脏病等。本文介绍不同国家/地区母乳中叶酸的含量、影响因素及其健康作用等,以期为婴幼儿配方食品的研发提供参考依据。Folic acid is a very important water-soluble vitamin in human milk,which is essential for embryonic development and growth.The folic acid in human milk often exists in the form of polyglutamic acid salts(≥ 4 glutamyl residues),such as 5-methyltetrahydrofolate.Folic acid deficiency may lead to birth defects such as neural tube defect and congenital heart disease.This article introduces the folic acid content in breast milk from different countries/regions,the factors influencing it and its health effects in order to provide a reference for the development of infant formula milk powder.

关 键 词：叶酸 母乳 神经管畸形 出生缺陷 婴幼儿配方乳粉 

分 类 号：TS252.1[轻工技术与工程—农产品加工及贮藏工程]