3D打印精准智齿冠周冲洗器清除菌斑的体外研究  

Removal of plaque biofilm by a 3D-printed precision pericoronal irrigator for impacted wisdom teeth:an in vitro study

作　　者：王晓婷 黄珍欣 郭维维 宋建业 周亮 韦柔漪 汪昆 WANG Xiaoting;HUANG Zhenxin;GUO Weiwei;SONG Jianye;ZHOU Liang;WEI Rouyi;WANG Kun(Department of Stomatology,Second Affiliated Hospital,Army Medical University(Third Military Medical University),Chongqing;No.9 Department,nstitute of Field Surgery,Army Medical Center of PLA/Daping Hospital of Third Military Medical University,Chongqing,China)

机构地区：[1]陆军军医大学(第三军医大学)第二附属医院口腔科,重庆 [2]陆军特色医学中心(第三军医大学大坪医院)野战外科研究部第九研究室,重庆

出　　处：《陆军军医大学学报》2025年第7期734-741,共8页Journal of Army Medical University

基　　金：重庆市器官智能生物制造工程研究中心开放项目(CQERC-OIBM20241013)。

摘　　要：目的研制一种冲洗头可直达阻生智齿冠周盲袋的精准化冲洗器,评估其对牙冠菌斑的清洁效能。方法3D打印4种不同面积比冠周软组织(0%、25%、50%、75%)覆盖的下颌智齿高位垂直阻生牙列模型及个性化精准智齿冠周冲洗器,不同覆盖面积比的模型随机分为3组,精准冠周冲洗组、常规冲洗组及刷牙组。分别在45、75 psi压强(1 psi=6894.76 Pa)下,对有菌斑生物膜的阻生智齿试验牙面进行清洁,采用Python软件分析清洁前后牙面图像并计算清洁率。结果在45 psi压强下,智齿冠周软组织覆盖面积比为50%、75%时,精准冠周冲洗组清洁率均显著高于刷牙组和常规冲洗组(P<0.05);冠周软组织覆盖面积比为0%、25%时,精准冠周冲洗组与刷牙组清洁率显著高于常规冲洗组(P<0.05);在75 psi压强下,冠周4种不同面积比软组织覆盖时,精准冠周冲洗组清洁率均显著高于常规冲洗组和刷牙组(P<0.05)。冠周软组织覆盖面积比为0%、25%及50%时,精准冠周冲洗组在75 psi压强下的清洁率显著高于在45 psi压强下的清洁率(P<0.05)。结论精准冠周冲洗器对垂直阻生智齿的清洁效能显著优于常规冲洗器及刷牙,是一种有效预防及治疗冠周炎的装置。Objective To prepare an advanced irrigation device equipped with a specialized nozzle designed to access the pericoronal blind sac of impacted wisdom teeth,and evaluate its efficacy in plaque removal.Methods 3D-printer was utilized to develop pericoronal models simulating mandibular wisdom teeth with high vertical impaction and varying soft tissue coverage(0%,25%,50%,and 75%,respectively)and personalized pericoronal irrigator.The obtained pericoronal models were randomly divided into 3 groups,treated with personalized precision pericoronal flushing,routine flushing and brushing,respectively,and,under a pressures of 45 psi or 75 psi(1 psi=6894.76 Pa),were performed to clean the test surfaces of plaquebiofilm-obstructed wisdom teeth,respectively.Images of the tooth surfaces were analyzed before and after cleaning,and the cleaning rate was calculated using Python software.Results For wisdom teeth with 50%and 75%pericoronal soft tissue coverage,at a pressure of 45 psi,the precision pericoronal flushing group demonstrated significantly higher cleaning rate when compared to the brushing and routine flushing groups(P<0.05).At 0%and 25%pericoronal soft tissue coverage,the precision pericoronal flushing and brushing groups exhibited significantly higher cleaning rates than the routine flushing group(P<0.05).Furthermore,at 75 psi,the precision pericoronal flushing group achieved a significantly higher cleaning rate across all 4 levels of pericoronal soft tissue coverage than both the routine flushing and brushing groups(P<0.05).Notably,the precision pericoronal flushing group at 75 psi obtained significantly higher cleaning rate than at 45 psi across 0%,25%,and 50%pericoronal soft tissue coverage(P<0.05).Conclusion The precision pericoronal irrigation device demonstrates significantly superior cleaning efficacy for vertically impacted mandibular third molars compared to conventional irrigation devices and manual tooth brushing.It is an effective device for preventing and treating pericoronitis.

关 键 词：3D打印 智齿 冲洗器 菌斑 体外研究 

分 类 号：R197.39[医药卫生—卫生事业管理] R780.1[医药卫生—公共卫生与预防医学] R781.4