一种吡啶酮染料中间体的合成  

Synthesis Process of a Dye Intermediate Derived from Pyridinone

作　　者：何江伟 陆军 龚斌彬 章燕 赵峰 张明省 HE Jiangwei;LU Jun;GONG Binbin;ZHANG Yan;ZHAO Feng;ZHANG Mingxing(Zhejiang Ruihua Chemical Co.,Ltd.,Shaoxing 312369,Zhejiang China;Zhejiang Runtu Co.,Ltd.,Shaoxing 312369,Zhejiang China)

机构地区：[1]浙江瑞华化工有限公司,绍兴312369 [2]浙江闰土股份有限公司,绍兴312369

出　　处：《染料与染色》2025年第1期21-24,共4页Dyestuffs and Coloration

摘　　要：本文研究了1-乙基-2-氧代-3-磺甲基-4-甲基-5-氨基甲酰基-6-羟基-吡啶酮的合成工艺,通过实验找到了该中间体的最佳合成路线。考察了反应pH值条件、反应温度、物料配比、反应时间等因素对合成结果的影响。在最优条件下,该中间体的液相纯度达到98%以上,总收率达到97%以上,且合成过程不产生废水,得到的产物无需提纯,直接用于活性染料的合成。The synthesis process of 5-(Aminocarbonyl)-1-ethyl-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinemethanesulfonic acid was studied.The optimum synthesis route of the intermediate was obtained by experiments.The effect factors such as reaction pH,reaction temperature,molar ratio and reaction time on the reaction was investigated.In the optimum condition,the HPLC purity was 98%,the yield was 97%.The synthesis process was wastewater-free,and the obtained product does not require purification and could be directly used in the synthesis of reactive dyes.

关 键 词：中间体 磺甲基化反应 吡啶酮衍生物 活性染料 合成 

分 类 号：TQ612.6[化学工程—精细化工]