硝黄散外敷治疗慢性放射性皮肤硬结性水肿验案举隅  

Experienced Cases of External Application of Xiaohuang Powder in the Treatment of Chronic Radiation-Induced Indurative Edema of Skin

作　　者：段孟希 郭智[2] 刘佳佳 李志辉 张露莎 刘丽坤[2] DUAN Mengxi;GUO Zhi;LIU Jiajia;LI Zhihui;ZHANG Lusha;LIU Likun(The First Clinical College,Shanxi University of Chinese Medicine,Taiyuan 030012 Shanxi,China;Department of Oncology,Shanxi Academy of Chinese Medicine,Taiyuan 030012 Shanxi,China)

机构地区：[1]山西中医药大学第一临床学院,山西太原030012 [2]山西省中医药研究院肿瘤科,山西太原030012

出　　处：《中医肿瘤学杂志》2025年第2期90-96,共7页Journal of Oncology in Chinese Medicine

基　　金：国家中医药传承创新中心的建设(编号:202203);山西省卫健委山西省医学科技创新团队项目(编号:2020TD04);肿瘤科四个一批创新团队(编号:1142-06)。

摘　　要：慢性放射性皮肤损伤(chronic radiation dermatitis,CRD)是肿瘤放射治疗过程中常见的一种并发症,目前对此尚无明确的治疗指南,故临床上常规处理CRD存在难愈合,易复发且不良反应较多等问题。有相关文献报道采用具有活血化瘀、清热解毒、消肿止痛等作用的中药外敷治疗可在一定程度上减轻患者放疗后局部皮肤的肿胀程度。本文从“火热毒邪”角度探讨放射性皮肤损伤的病因病机及治疗原则,提出对于硬结性水肿可在“活血祛瘀、解毒消肿”的治疗原则下,选用硝黄散进行外敷治疗,并附验案2则加以佐证。Chronic radiation dermatitis(CRD)is a common complication during radiotherapy of tumors.Currently,there is no clear treatment guideline for it.Therefore,the conventional clinical treatment of CRD has problems such as difficult wound-healing,easy recurrence,and more adverse reactions.Relevant literature reports that external application of traditional Chinese medicine with the effects of promoting blood circulation to remove blood stasis,clearing heat and detoxifying,and relieving swelling and pain can to some extent reduce the degree of local skin swelling in patients after radiotherapy.This paper explored the etiology,pathogenesis,and treatment principles of radiation-induced skin injury from the perspective of“fire-heat toxin”.It was proposed that for indurative edema,Xiaohuang Powder could be selected for external application treatment under the principle of“promoting blood circulation to remove stasis,detoxifying and reducing swelling”,with two cases attached for verification.

关 键 词：放射性皮肤损伤 硬结性水肿 中医外治法 

分 类 号：R273[医药卫生—中西医结合] R730.52[医药卫生—中医肿瘤科] R758.13[医药卫生—中医学] R275.9